Protein Alignment Vha100-4 and atp6v0a1a

DIOPT Version :10

• Sequence 1: NP_650720.1
• Gene: Vha100-4 / 42214
• FlyBaseID: FBgn0038613
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: XP_005163855.2
• Gene: atp6v0a1a / 324307
• ZFINID: ZDB-GENE-030131-3027
• Length: 840
• Species: Danio rerio
• Alignment Length: 859
• Identity: 413/859 - (48%)
• Similarity: 571/859 - (66%)
• Gaps: 64/859 - (7%)

  Fly    16 IFRSEVMSLVQMYLQPEAAYDTIAALGEVGCVQFRDLNAKINAQQRKFIGEVRRCDELERRIRYV 80
            :||||.|:|.|::||.|:||..::.|||:|.|||||||..:||.||||:.|||||:|::|::|:|
Zfish     4 LFRSEEMTLAQLFLQSESAYCCVSELGEIGMVQFRDLNPDVNAFQRKFVNEVRRCEEMDRKLRFV 68

  Fly    81 TAELNKEGHKVLDLMDDFPPAPQPREIIDLELHLEKTETEILELAANNVNLQTSYLELSEMIQVL 145
            ..|:.|....::|..:: |..|.||::||||...||.|.|:.|:..|...|:.::|||:|:..:|
Zfish    69 EKEIKKANIPIVDTGEN-PEVPFPRDMIDLEATFEKLENELKEINTNQEALKKNFLELTELKHIL 132

  Fly   146 ERTDQFFSDQESHNFDLNKMGTHRDPEKSNG----HLGFVAGVISREREYAFERMLWRISRGNVF 206
            .||.|||.:.|..:. |.:..|..||.:...    .||||||||.|||...|||||||:.|||||
Zfish   133 RRTQQFFDEMEDPSL-LEESSTLLDPNEVGRAAPLRLGFVAGVIGRERIPTFERMLWRVCRGNVF 196

  Fly   207 VRRCDVDVALTDPKTGNVLHKSVFVVFFQGDQLQARIRKVCTGFHAHMYPCPSSHSERQEMVKNV 271
            :|:.|::..|.||.||:.:|||||::|||||||:.|::|:|.||.|.:||||.:..||:||...|
Zfish   197 LRQADIEDPLEDPATGDNVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMAAGV 261

  Fly   272 RTRLEDLQVIINQTSDHRTCVLQAALKQLPTWSAMVKKMKGIYHTLNLFNVDLGSKCLIGEGWVP 336
            .||::|||:::|||.|||..|||||.|.:..|...|:|||.|||||||.|:|:..||||.|.|.|
Zfish   262 NTRIDDLQMVLNQTEDHRQRVLQAAAKTVRVWFIKVRKMKAIYHTLNLCNIDVTQKCLIAEIWCP 326

  Fly   337 KRELELVEVALAAGSASVGSTVPSFINVLDTKKEPPTHFRTNKFTRGFQNLIDAYGIAGYREVNP 401
            ..:|:.::.||..|:...||||||.:|.:.||:.|||:.:|||||.|||:::|||||:.|||:||
Zfish   327 VSDLDSIQFALRRGTERSGSTVPSILNRMQTKQTPPTYNKTNKFTSGFQSIVDAYGISNYREMNP 391

  Fly   402 GLYTCITFPFLFAVMFGDMGHGTILFLLGLWMVIDEKRL-SKKRGGEIWNIFFAGRYIIMLMGLF 465
            ..||.|||||||||||||:|||.::....|::|:.|.|| ::|...|::::.|||||||:|||||
Zfish   392 APYTIITFPFLFAVMFGDLGHGVLMTCAALYLVLRESRLIAQKNDSEMFSMVFAGRYIILLMGLF 456

  Fly   466 AMYTGFHYNDIFSKSINVFGTRW--------------VNVYNRTTVLTNPTLQLNPSVAT--RGV 514
            :||||..|||.||||:|:||:.|              ..|..::.|     |||||:|..  .|.
Zfish   457 SMYTGIIYNDCFSKSLNIFGSGWSVRPMFGEKGDNWTFAVLEKSNV-----LQLNPAVPNVFTGP 516

  Fly   515 YPMGIDPIWQSASNKIIFLNTYKMKLSIIFGVLHMVFGVCMSVENFVFFKKYAYIILQFVPQVLF 579
            ||:||||||..|:||:.|||::|||:|||.||:||:|||.:|:.|.::|:|...|.|.|:|:::|
Zfish   517 YPVGIDPIWNIATNKLTFLNSFKMKMSIILGVIHMIFGVSLSLFNHLYFRKPLNIYLGFIPEIIF 581

  Fly   580 LLLMFGYMCFMMFYKWVKYSPTTDVEADTPGCAPSVLIMFIDMVLF--KTETALPGCDVNMFPIQ 642
            ::.:|||:..::||||:.|      :|.:...|||:||.||:|.||  ...|..|     .:..|
Zfish   582 MVSLFGYLVLLIFYKWIAY------DAKSSRVAPSLLITFINMCLFSYNDPTNKP-----FYTGQ 635

  Fly   643 KNLEMIFLVVALLCIPWILLGKPLYIKYQ---RRNRPA----------GPVEEVDEIVEKIEVTT 694
            ..::.:.:::||.|:|.:|:.|.|.::.|   ||:...          ||.|:..||::..:::.
Zfish   636 VVIQCLLVIIALSCVPCMLIVKTLVMRRQHLWRRHLGTQNFGGIHVGNGPTEDEAEIIQHDQLSQ 700

  Fly   695 GKEIIITEVAEAHESGGHSEEDDEPMSEIWIHQAIHTIEYILSTISHTASYLRLWALSLAHAQLS 759
            ..|          |....|||:....::..:|||||||||.|..||:||||||||||||||||||
Zfish   701 NTE----------EEPEPSEEEVFNFADEAVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLS 755

  Fly   760 EVLWTMVLAMGLQMNGYVGAIGLFFIFAVWEFFTIAIMVMMEGLSAFLHTLRLHWVEFMSKFYVG 824
            ||||:||:.|||....:.|.|.|..||..:...|:.|:::|||||||||.||||||||.:|||.|
Zfish   756 EVLWSMVMHMGLSSRSFGGFIFLSIIFCFFAVLTVFILLVMEGLSAFLHALRLHWVEFQNKFYTG 820

  Fly   825 NGYPFTPFSFKDIL 838
            .|:.|.||:|..||
Zfish   821 QGFKFMPFTFDSIL 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-4	NP_650720.1	V_ATPase_I	39..834	CDD:460232	398/830 (48%)
atp6v0a1a	XP_005163855.2	None