Protein Alignment Vha100-4 and vph1

DIOPT Version :10

• Sequence 1: NP_650720.1
• Gene: Vha100-4 / 42214
• FlyBaseID: FBgn0038613
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_594219.2
• Gene: vph1 / 2542310
• PomBaseID: SPAC16E8.07C
• Length: 831
• Species: Schizosaccharomyces pombe
• Alignment Length: 870
• Identity: 341/870 - (39%)
• Similarity: 482/870 - (55%)
• Gaps: 91/870 - (10%)

  Fly    13 SNSIFRSEVMSLVQMYLQPEAAYDTIAALGEVGCVQFRDLNAKINAQQRKFIGEVRRCDELERRI 77
            |.|:||||.:||||:||..|:|...::||||:..:.|:|||..:.|.||.|:.|:||..:.||.:
pombe     2 SPSLFRSEEVSLVQLYLPTESARPIMSALGELSTIHFKDLNPDVVAFQRSFVREIRRLTDTERLL 66

  Fly    78 RYVTAELNKEGHKVLDLMDDFPPA----PQPREIIDLELHLEKTETEILELAANNVNLQTSYLEL 138
            ||:.:|::..|..|.|  .:.||:    .:...|.|:...:.:.|..:.:|..::..|:..||:.
pombe    67 RYLHSEIDLNGIHVPD--HNLPPSYESVLESSTIEDIIERITRLEARVRQLVESSQLLEARYLQQ 129

  Fly   139 SEMIQVLERTDQFFS------DQESHNF---------------------DLNKMGTHRDPEKS-- 174
            .|...||.:.|.|||      |...:|:                     :|...||....|.|
pombe   130 LEFANVLTKADAFFSKSGNTVDPLRNNYETSSIFSGEDDTTAPLIENALELGTTGTFDSEETSPQ 194

  Fly   175 -NGHLGFVAGVISREREYAFERMLWRISRGNVFVRRCDVDVALTDPKTGNVLHKSVFVVFFQGDQ 238
             |..|.||:|:|...:....||:|||..|||:|:.:...|.:|......|. .|::|:|...|.|
pombe   195 MNTTLDFVSGIIPTVKFQFLERILWRTLRGNLFIHQVRADDSLIHGAEKNE-EKTIFLVIAHGTQ 258

  Fly   239 LQARIRKVCTGFHAHMYPCPSSHSERQEMVKNVRTRLEDLQVIINQTSDHRTCVLQAALKQLPTW 303
            :..||||:.....|.::|.......|...::.....:.||..::..|.......|....:.:..|
pombe   259 ILLRIRKISESLGATLFPVEEDAPGRTSQIQQANVSISDLNAVLENTRSALYTELTFIAEHISAW 323

  Fly   304 SAMVKKMKGIYHTLNLFNVDLGSKCLIGEGWVPKRELELVEVALAAGSASVGSTVPSFINVLDTK 368
            .|::.|.|.::..:||||.|...||||.|||.|...|.:|:..|...|....|..|:.:||:.|.
pombe   324 EAVLHKDKTVFQVMNLFNYDQNHKCLIAEGWCPTANLPMVQKTLRNISDLTDSQAPTILNVVHTS 388

  Fly   369 KEPPTHFRTNKFTRGFQNLIDAYGIAGYREVNPGLYTCITFPFLFAVMFGDMGHGTILFLLGLWM 433
            ::|||:||.||||.|||::||:||||.|||||.|:...:|||||||:||||:|||.|:..:.|..
pombe   389 EQPPTYFRVNKFTEGFQSIIDSYGIATYREVNHGIVAIVTFPFLFAIMFGDLGHGAIMASVALMF 453

  Fly   434 VIDEKRL-SKKRGGEIWNIFFAGRYIIMLMGLFAMYTGFHYNDIFSKSINVFGTRWVNVYNRTTV 497
            |:.||.| :||...||..:.|.||||::|||||:||.||.|||:|||.:::|.:|||........
pombe   454 VLYEKTLGAKKDLDEIVGMVFYGRYIVLLMGLFSMYVGFVYNDLFSKPMSIFSSRWVWPVKSEEA 518

  Fly   498 LTNPTLQLNPSVATRGVYPMGIDPIWQSASNKIIFLNTYKMKLSIIFGVLHMVFGVCMSVENFVF 562
            :.. .:|:       |.||:||||.|.||.|.::|:|:||||||||.||:||.|.:.:|:.|:.|
pombe   519 IAR-AVQV-------GTYPIGIDPTWHSADNNLLFMNSYKMKLSIILGVIHMTFCLFLSLSNYRF 575

  Fly   563 FKKYAYIILQFVPQVLFLLLMFGYMCFMMFYKWVKYSPTTDVEADTPGCAPSVLIMFIDMVLFKT 627
            ||:...|...|||.::||..:|||:...:.|||.......|::      .||:|.|.|.|.|
pombe   576 FKRKLDIYAVFVPSLIFLEAIFGYLVITIVYKWCIDWKAKDLQ------PPSLLNMLILMFL--- 631

  Fly   628 ETALPG-CDVNMFPIQKNLEMIFLVVALLCIPWILLGKPLYI---------KYQRRNRPAGPVEE 682
               .|| .:..::|.||.|::..::.||:|:||:|:.||..:         |||..|.....|:|
pombe   632 ---SPGTLEDQLYPGQKYLQVGLVIAALICVPWLLIVKPFVLWRRHSNEENKYQSLNSDLPNVDE 693

  Fly   683 VDEIVEKIEVTTGKEIIITEVAEAHESGGHSEEDDEP--MSEIWIHQAIHTIEYILSTISHTASY 745
            .|.::                  |.:|   .|:..||  :.|:.|||.|||||:.|..:||||||
pombe   694 ADALM------------------AVDS---QEKQAEPFELGEVVIHQVIHTIEFCLGCVSHTASY 737

  Fly   746 LRLWALSLAHAQLSEVLWTMVLAMGLQMNGYVGAIGLFFIFAVWEFFTIAIMVMMEGLSAFLHTL 810
            ||||||||||.|||.|||.|.||.|.:|.|.||:|.:..:|..|...|..::|.|||.||.||:|
pombe   738 LRLWALSLAHNQLSSVLWNMTLANGFRMTGIVGSIFVVILFGFWFIATCVVLVAMEGTSAMLHSL 802

  Fly   811 RLHWVEFMSKFYVGNGYPFTPFSFK 835
            ||||||.|||.:.|.||.||||:||
pombe   803 RLHWVEGMSKHFEGEGYAFTPFTFK 827

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-4	NP_650720.1	V_ATPase_I	39..834	CDD:460232	325/841 (39%)
vph1	NP_594219.2	V_ATPase_I	28..826	CDD:460232	325/841 (39%)