Protein Alignment Vha100-4 and Vha100-1

DIOPT Version :10

• Sequence 1: NP_650720.1
• Gene: Vha100-4 / 42214
• FlyBaseID: FBgn0038613
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: XP_061502235.1
• Gene: Vha100-1 / 1274390
• VectorBaseID: AGAMI1_005601
• Length: 868
• Species: Anopheles gambiae
• Alignment Length: 870
• Identity: 459/870 - (52%)
• Similarity: 591/870 - (67%)
• Gaps: 59/870 - (6%)

  Fly    15 SIFRSEVMSLVQMYLQPEAAYDTIAALGEVGCVQFRDLNAKINAQQRKFIGEVRRCDELERRIRY 79
            |:||||.|||.|::||.||||..::.|||:|.|||||||..:||.||||:.|||||||:||::||
Mosquito     3 SLFRSEEMSLCQLFLQSEAAYACVSELGELGLVQFRDLNPDVNAFQRKFVNEVRRCDEMERKLRY 67

  Fly    80 VTAELNKEGHKVLDLMDDFPPAPQPREIIDLELHLEKTETEILELAANNVNLQTSYLELSEMIQV 144
            :..|:.|:|..:|| ..:.|.||||||:||||...||.|.|:.|:..|...|:.:||||:|:..:
Mosquito    68 LEKEIKKDGIPMLD-TGESPEAPQPREMIDLEATFEKLENELREVNQNAEALKRNYLELTELKHI 131

  Fly   145 LERTDQFFSD--------QESHNFDLNKMGTHRDPEK------------------SNGHLGFVAG 183
            |.:|..||.:        .::.|.......:||:.|:                  .|..||||||
Mosquito   132 LRKTQVFFDEAVYTGNVPNKTRNRYQQMADSHREEEQVNLLGEEGIRAGGAGAQGQNLKLGFVAG 196

  Fly   184 VISREREYAFERMLWRISRGNVFVRRCDVDVALTDPKTGNVLHKSVFVVFFQGDQLQARIRKVCT 248
            ||.|||..||||||||..|||||:|:..::..|.||..|:.::||||::|||||||:.|::|:|.
Mosquito   197 VILRERLPAFERMLWRACRGNVFLRQAMIEDPLEDPSNGDKVYKSVFIIFFQGDQLKTRVKKICE 261

  Fly   249 GFHAHMYPCPSSHSERQEMVKNVRTRLEDLQVIINQTSDHRTCVLQAALKQLPTWSAMVKKMKGI 313
            ||.|.:||||.:.::|:||...|.||:|||..::.||.|||..||.||.|.|..|...|:|:|.|
Mosquito   262 GFRATLYPCPEAPTDRREMAMGVMTRIEDLHTVLGQTQDHRHRVLVAAAKNLKNWFVKVRKIKAI 326

  Fly   314 YHTLNLFNVDLGSKCLIGEGWVPKRELELVEVALAAGSASVGSTVPSFINVLDTKKEPPTHFRTN 378
            ||||||||:|:..||||.|.|||..:.|.:::||..|:...||:||..:|.::|.::|||:.|||
Mosquito   327 YHTLNLFNLDVTQKCLIAECWVPLLDFETIQIALRRGTERSGSSVPPILNRMETFEDPPTYNRTN 391

  Fly   379 KFTRGFQNLIDAYGIAGYREVNPGLYTCITFPFLFAVMFGDMGHGTILFLLGLWMVIDEKRL-SK 442
            |||..||.||:|||:|.|||:||..||.|||||||||||||:|||||:.|.|||||:.||.| :|
Mosquito   392 KFTHAFQALINAYGVASYREMNPAPYTIITFPFLFAVMFGDLGHGTIMALFGLWMVLKEKPLAAK 456

  Fly   443 KRGGEIWNIFFAGRYIIMLMGLFAMYTGFHYNDIFSKSINVFGTRWVNVYNRTTVLTNPTLQLNP 507
            |...|||||||.|||||.|||:|:|||||.||||||||:||||:.|...||.:||::|..|||||
Mosquito   457 KSDNEIWNIFFGGRYIIFLMGVFSMYTGFVYNDIFSKSLNVFGSAWSTNYNTSTVMSNKALQLNP 521

  Fly   508 SVATRGV------YPMGIDPIWQSAS-NKIIFLNTYKMKLSIIFGVLHMVFGVCMSVENFVFFKK 565
                :|:      ||.|:||:||.|. |||||.|.||||:||||||:||:|||.:.:.|..:||.
Mosquito   522 ----KGMDYAQTPYPFGLDPVWQVAPLNKIIFQNAYKMKISIIFGVIHMLFGVFVGLFNHRYFKN 582

  Fly   566 YAYIILQFVPQVLFLLLMFGYMCFMMFYKWVKYSPT-TDVEADTPGCAPSVLIMFIDMVLFKTET 629
            ...|..:|:|||:||:.:|.||..:||.||||||.: ||| ..:.|||||:||.||:|||||...
Mosquito   583 KMAIYCEFIPQVIFLVFLFFYMTLLMFIKWVKYSASATDV-VYSEGCAPSILITFINMVLFKAPD 646

  Fly   630 ALPG-CDVNMFPIQKNLEMIFLVVALLCIPWILLGKPLYIKYQRR---NRPAGPVEEVDEIVEKI 690
            ...| |...||..|..|:...:||||||:||:||.||:.|...|:   ::|..|....:...:.:
Mosquito   647 ENTGDCSPYMFAGQSGLQKFLVVVALLCVPWMLLAKPILIMRGRKEAAHQPIAPYSNENGDADGL 711

  Fly   691 E-------VTTGKEIIITEVAEAHESGGHSEEDDEPMSEIWIHQAIHTIEYILSTISHTASYLRL 748
            .       ...|::       .|.:.||....|:|.||||:|||.||||||:|.::|||||||||
Mosquito   712 NQHNNGAGTQAGQQ-------PAQQQGGGHGHDNEEMSEIFIHQGIHTIEYVLGSVSHTASYLRL 769

  Fly   749 WALSLAHAQLSEVLWTMVLAMGLQMNGYVGAIGLFFIFAVWEFFTIAIMVMMEGLSAFLHTLRLH 813
            ||||||||||:||||.|||..||:.:|::|.|.|:.:||.|...|:.|:|:||||||||||||||
Mosquito   770 WALSLAHAQLAEVLWNMVLQNGLKQDGWIGGIALWAVFAFWAVLTVGILVLMEGLSAFLHTLRLH 834

  Fly   814 WVEFMSKFYVGNGYPFTPFSFKDIL 838
            ||||.||||.|.||.|.||||:.||
Mosquito   835 WVEFQSKFYAGLGYAFQPFSFEVIL 859

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-4	NP_650720.1	V_ATPase_I	39..834	CDD:460232	440/840 (52%)
Vha100-1	XP_061502235.1	None