Protein Alignment Vha100-4 and Atp6v0a2

DIOPT Version :9

• Sequence 1: NP_650720.1
• Gene: Vha100-4 / 42214
• FlyBaseID: FBgn0038613
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_446227.2
• Gene: Atp6v0a2 / 116455
• RGDID: 621006
• Length: 856
• Species: Rattus norvegicus
• Alignment Length: 865
• Identity: 368/865 - (42%)
• Similarity: 541/865 - (62%)
• Gaps: 70/865 - (8%)

  Fly    15 SIFRSEVMSLVQMYLQPEAAYDTIAALGEVGCVQFRDLNAKINAQQRKFIGEVRRCDELERRIRY 79
            |:||||.|.|.|::||...||:.::||||.|.|||||||..:::.||||:|||:||:||||.:.|
  Rat     3 SLFRSESMCLAQLFLQSGTAYECLSALGEKGLVQFRDLNQNVSSFQRKFVGEVKRCEELERILVY 67

  Fly    80 VTAELNK------EGHKVLDLMDDFPPAPQPREIIDLELHLEKTETEILELAANNVNLQTSYLEL 138
            :..|:.:      ||       :..||||..:.:::::..|:|.|.|:.|:..|...|:.:.|||
  Rat    68 LVQEITRADIPLPEG-------EASPPAPPVKHVLEMQEQLQKLEVELREVTKNKEKLRKNLLEL 125

  Fly   139 SEMIQVLERTDQFF--------SDQESHNFDLNKMGTHRDPEKSNGHLGFVAGVISREREYAFER 195
            .|...:|..|..|.        :.:|....:.:.:..:...::....||||:|:|.:.:..||||
  Rat   126 VEYTHMLRVTKTFLKRNVEFEPTYEEFPALESDSLLDYSCMQRLGAKLGFVSGLIQQGKVEAFER 190

  Fly   196 MLWRISRGNVFVRRCDVDVALTDPKTGNVLHKSVFVVFFQGDQLQARIRKVCTGFHAHMYPCPSS 260
            ||||..:|...|...::|.||.||:||.|:...||::.|.|:|:..:::|:|..:|.|:||.|::
  Rat   191 MLWRACKGYTIVTYAELDEALEDPETGEVIKWYVFLISFWGEQIGHKVKKICDCYHCHIYPYPNT 255

  Fly   261 HSERQEMVKNVRTRLEDLQVIINQTSDHRTCVLQAALKQLPTWSAMVKKMKGIYHTLNLFNVDLG 325
            ..||:|:.:.:.||::||..::::|.|:...||..|.:.:.:....|:|||.|||.||:.:.|:.
  Rat   256 AEERREIQEGLNTRIQDLYTVLHKTEDYLRQVLCKAAESVCSRVIQVRKMKAIYHMLNMCSFDVT 320

  Fly   326 SKCLIGEGWVPKRELELVEVALAAGSASVGSTVPSFINVLDTKKEPPTHFRTNKFTRGFQNLIDA 390
            :||||.|.|.|:.:|..:..||..||...|:|:|||:|.:.||:.|||..||||||.||||::||
  Rat   321 NKCLIAEVWCPEVDLPGLRRALEEGSRESGATIPSFMNTIPTKETPPTLIRTNKFTEGFQNIVDA 385

  Fly   391 YGIAGYREVNPGLYTCITFPFLFAVMFGDMGHGTILFLLGLWMVIDEK--RLSKKRGGEIWNIFF 453
            ||:..||||||.|:|.|||||||.|||||:|||.::||..|.:|::|.  |||:.:  ||..:||
  Rat   386 YGVGSYREVNPALFTIITFPFLFGVMFGDLGHGFVMFLFALLLVLNENHPRLSQSQ--EILRMFF 448

  Fly   454 AGRYIIMLMGLFAMYTGFHYNDIFSKSINVFGTRWVNV------------------YNRTTVLTN 500
            .||||::|||||::|||..|||.||||:|:||:.| ||                  :|.:|:..:
  Rat   449 DGRYILLLMGLFSVYTGLIYNDCFSKSLNLFGSGW-NVSAMYSSSHSPEEQRKMVLWNDSTIRHS 512

  Fly   501 PTLQLNPSV--ATRGVYPMGIDPIWQSASNKIIFLNTYKMKLSIIFGVLHMVFGVCMSVENFVFF 563
            .||||:|::  ..||.||.||||||..|:|::.|||::|||:|:|.|:.||.|||.:.:.|.:.|
  Rat   513 RTLQLDPNIPGVFRGPYPFGIDPIWNLATNRLTFLNSFKMKMSVILGIFHMTFGVILGIFNHLHF 577

  Fly   564 KKYAYIILQFVPQVLFLLLMFGYMCFMMFYKWVKYSPTTDVEADTPGCAPSVLIMFIDMVLF-KT 627
            :|...|.|..||::||:|.:|||:.||:.|||:.||..|..|      |||:||.||:|.|| .:
  Rat   578 RKKFNIYLVSVPEILFMLCIFGYLIFMIIYKWLAYSAETSRE------APSILIEFINMFLFPSS 636

  Fly   628 ETALPGCDVNMFPIQKNLEMIFLVVALLCIPWILLGKPLYIKYQRRNRPA-GPVEEVDEIVEKIE 691
            ||.      .::|.|.:::.:.|.:.:|.:|.:.|||||::.:....|.. |.......:|.|
  Rat   637 ETH------GLYPGQAHVQKVLLALTVLAVPVLFLGKPLFLLWLHNGRSCFGVSRSGYTLVRK-- 693

  Fly   692 VTTGKEIIITEVAEAHESGGHSEEDDEPMS-------EIWIHQAIHTIEYILSTISHTASYLRLW 749
             .:.:|:.:....:..|.....||....|:       ||.:.||||:|||.|..||:||||||||
  Rat   694 -DSEEEVSLLGSQDIEEGNNRMEEGCREMTCEEFNFGEILMTQAIHSIEYCLGCISNTASYLRLW 757

  Fly   750 ALSLAHAQLSEVLWTMVLAMGLQMNGYVGAIGLFFIFAVWEFFTIAIMVMMEGLSAFLHTLRLHW 814
            ||||||||||:|||.|::.:||:::...|.:.|..:...:...|:.|:::|||||||||.:||||
  Rat   758 ALSLAHAQLSDVLWAMLMRVGLRVDNTYGVLLLLPVMTFFAVLTVFILLVMEGLSAFLHAIRLHW 822

  Fly   815 VEFMSKFYVGNGYPFTPFSF 834
            |||.:|||||.|..|.||||
  Rat   823 VEFQNKFYVGAGTKFVPFSF 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-4	NP_650720.1	NtpI	17..836	CDD:224188	367/863 (43%)
		V_ATPase_I	40..834	CDD:279793	354/838 (42%)
Atp6v0a2	NP_446227.2	NtpI	5..839	CDD:224188	363/858 (42%)
		V_ATPase_I	28..839	CDD:279793	352/835 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D164762at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010