Protein Alignment CG14309 and Hpse2

DIOPT Version :10

• Sequence 1: NP_650718.2
• Gene: CG14309 / 42212
• FlyBaseID: FBgn0038611
• Length: 966
• Species: Drosophila melanogaster
• Sequence 2: NP_001074726.1
• Gene: Hpse2 / 545291
• MGIID: 2685814
• Length: 592
• Species: Mus musculus
• Alignment Length: 604
• Identity: 126/604 - (20%)
• Similarity: 197/604 - (32%)
• Gaps: 215/604 - (35%)

  Fly     5 CLALLGLAVVCF------------------------ADTLVQLHVN--RPYNDVNEKFVSFAVRP 43
            ||||:.|.:...                        ..||:.|.|:  .|...|||.|:|..:.|
Mouse    21 CLALVALFLALLLHLSLSFHAGNRRPLPVDRATGLKEKTLILLDVSTKNPVRTVNENFLSLQLDP 85

  Fly    44 EDLYDA-LDGKNRKAVTNLANLLGDAHIKFVG---DFYFASNAPTRLRNPTK------------- 91
            ..::|. ||..:.|.:..||..|..|.::|.|   ||....|    ||||.|
Mouse    86 SIIHDGWLDFLSSKRLVTLARGLSPAFLRFGGKRTDFLQFQN----LRNPAKSRGGPGPDYYLKN 146

  Fly    92 ----II--------WKG------------------------------FNRWSRAVNWTMIIPVPY 114
                |:        .||                              .|.:|..:.....:...|
Mouse   147 YEDDIVRSDVALDKQKGCKIAQHPDVMLELQREKASQMHLVLLKEQYSNTYSNLILTARSLDKLY 211

  Fly   115 --------------------APDDWDSMHTLKILNTS----YMVGITDCIWQLGTD--------- 146
                                ..:.|:|...|.:|..|    |.:.     |:||.:
Mouse   212 NFADCSGLHLIFALNALRRNPNNSWNSSSALSLLKYSASKKYNIS-----WELGNEPNNYRSIHG 271

  Fly   147 ---FGTSRAKDYVQELRTLKLMTDTFKPYVDDWRLMGADIS----------------AGSSADET 192
               .|:...|||:|    ||.:....:.| ....|.|.:|.                |||:.|..
Mouse   272 RAVNGSQLGKDYIQ----LKSLLQPIRVY-SRASLYGPNIGRPRKNVIALLDGFMKVAGSTVDAV 331

  Fly   193 ---KRYVDMSKDLNTAFGWTQPANMLPKSSLGSYLYDSDPALRTLQQQRVP---LWL--TLPEER 249
               ..|:|         |.........|:.|...|.|....::.:.....|   :||  .:....
Mouse   332 TWQHCYID---------GRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKIWLEGVVTTSA 387

  Fly   250 SSQRLVGDETTDALRWAQTMGDAAASGFDVIFKRM-------NLVDFERPNFS----LYVTALFK 303
            .....:.|.......|..|:|..|..|.||:.:..       :|||   .||:    .:::.|:|
Mouse   388 GGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVD---QNFNPLPDYWLSLLYK 449

  Fly   304 KVMGSRVFPA---------RPLNAFAPSNKLYTHCA-----NAVSGGLAFMVVNTEEQPTTITVK 354
            :::|.:|...         ||........::|.||.     |.|.|.:...::|.......|  |
Mouse   450 RLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSITLFIINLHRSRKKI--K 512

  Fly   355 STSSLSSSEIWQYVLTGHDQR------VQLNNVRLHL--NTTLRPLIKPIDPTKPLQ----LITP 407
            ...:|....:.||:|..:.|.      ||||...|.:  :.|| |.:||    :||:    |:.|
Mouse   513 LAGTLRDKLVHQYLLQPYGQEGLKSKSVQLNGQPLVMVDDGTL-PELKP----RPLRAGRTLVIP 572

  Fly   408 SMAVSFWVLPDVNLEHCQF 426
            .:.:.|:|:.:||...|::
Mouse   573 PVTMGFYVVKNVNALACRY 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14309	NP_650718.2	None
Hpse2	NP_001074726.1	Glyco_hydro_79n	<208..408	CDD:461010	38/218 (17%)