Protein Alignment CG14309 and LOC11175584

DIOPT Version :10

• Sequence 1: NP_650718.2
• Gene: CG14309 / 42212
• FlyBaseID: FBgn0038611
• Length: 966
• Species: Drosophila melanogaster
• Sequence 2: XP_061508902.1
• Gene: LOC11175584 / 11175584
• VectorBaseID: AGAMI1_001258
• Length: 1128
• Species: Anopheles gambiae
• Alignment Length: 1172
• Identity: 251/1172 - (21%)
• Similarity: 440/1172 - (37%)
• Gaps: 354/1172 - (30%)

  Fly    21 VQLHVNRPYNDVNEKFVSFAVRPEDLYDALDGKNRKAVTNLANLLGDAHIKFVGD----FYFASN 81
            |.::..|..|.:.::|:||:.:|:|::|.......:....:|..||...:|.:.|    ....:.
Mosquito    51 VSVNTRRLANVLGDEFISFSAKPQDIFDGQGNPITETSFLMAQSLGGTFLKVIADSSQLHLQTTG 115

  Fly    82 APTRLRNPTKI--------IWKGFNRWSRAVNWTMIIPVPYAPD--DWDSMHTLKILNTSYMVGI 136
            ..:.:.||..:        .|:.|..|:|..|...:..:.|..|  .||....|:||..:..:||
Mosquito   116 GQSVIGNPDDVELVQISASAWQAFYDWARRANILPVFVLDYPTDGGQWDVKKALRILTAASALGI 180

  Fly   137 TDCIWQLGTDFGTSRAKDYVQELRTLKLMTDTFKPYVDDWRLMGADISAGSSADETKRYVDMSKD 201
            .:|.||||........| |..:|||.:.|...|..  .:|.::.::::......|..:|...:.|
Mosquito   181 DECRWQLGNGLVKDGVK-YADDLRTFRTMLQAFPK--QNWTVVASELNPQLVPLEDVQYFHANGD 242

  Fly   202 LNTAFGWTQPANMLPKSSLGSYLYDS----------DPALRTLQQQRVPLWLTLPEE--RSSQRL 254
                       :::...::....|||          |..||.|.:||:|:||.|..:  ||....
Mosquito   243 -----------SLVDAITISRPRYDSAAWNYTTLQRDIHLRGLSKQRLPIWLDLVADYNRSEVEA 296

  Fly   255 VGD-ETT-----------DALRWAQTMGDAAASGFDVIFKRMNLVDFERPNFSLYVTALFKKVMG 307
            .|| |:|           :.|.:|:|:|:||..|...:|:.:...|.::.:....::||:|:.:|
Mosquito   297 SGDTESTAAPTCCKSCVQEGLDYARTLGEAARGGISAVFQPLQRDDIQQYSLHYLISALYKQTVG 361

  Fly   308 SRVFPAR----PLNAFAPSNKLYTHCANAVSGGLAFMVVNTEEQ-PTTITVKSTSSLSSSEIWQY 367
            .:|||..    |.........:|.:|....:|.|..::||.||: .|..|:|..:...||.:..:
Mosquito   362 HKVFPVHFNLLPAGEKPGQTSVYAYCTRNRTGSLTLVLVNGEEEGATNATIKLLTRSLSSPVELF 426

  Fly   368 VLTGHDQRVQLNNVRLHLNTTLRPLIKPIDPTKPLQLIT-------PSMAVSFWVLPDVNLEHCQ 425
            :|:..|.:..:||:.|....|..|  ..|:|.|.:..:|       |:..:.|.|:|.|.:..|:
Mosquito   427 LLSVQDGQPMVNNLPLDATATTTP--PSIEPVKAVTTLTHGVSFYVPAQTILFAVIPGVQVRECR 489

  Fly   426 FTEIEAGDSSGESSKEKRR-SFRYSSADRLLQRLIEE---------------------------- 461
                  .|:..|..|..|. ....:|.|.||:.||.|
Mosquito   490 ------NDALPERKKLPRELQHDRTSTDLLLEELIGELLANAPRDTLQRRRRSLGEQDKPTIKAN 548

  Fly   462 -----------------------TAV--------------ARGSVQS-SINRNRRFVVDKEETSQ 488
                                   :||              |||..|: :..|.:|.:.:||:.|:
Mosquito   549 KKWKRFHARFTDASQSDGLAESLSAVLADAQSTVGPTERTARGPRQTQAYKRQQRRIRNKEKRSE 613

  Fly   489 TLLDRLLDHFKDDGPLKRDVGDEVNKSKEQAIKPHKALAWLYQVLEHTR---DMGKKRERRDTSS 550
            ....:.:.|...:...:|....::.|::..|..||:.:        |.|   .|..|.|.|.|
Mosquito   614 MRNLKKMKHPLREARRERSKRGDLLKARRSAAHPHRRI--------HQRLLNRMSAKLESRKT-- 668

  Fly   551 YSGPFFYNRQGKKTALTKKITEIRKPEKKNKPLF--DFDEFDEEKFFKRIGEKSEEIPTYTRLPE 613
                       |:::|.:.:.|        .|.|  ..||.||      :|::|:       .|.
Mosquito   669 -----------KRSSLAEAVNE--------PPNFGAGSDEQDE------LGQRSD-------FPL 701

  Fly   614 GDVHLKHIE--TVDGEVE---------NEEELEREVPKKRRTKS--------KSQLKIIQRE--- 656
            |||||...:  ..|||||         :::.:|..:.:::::.|        :.::.:.||:
Mosquito   702 GDVHLVISKGGNGDGEVEYVPTDDDDDDDDAVEVGMVERKQSWSGARHRPAIRRRISVNQRDFYR 766

  Fly   657 -----DKEDEQEQEPEQTE-GRPK-LRLLPTEFFEALPAPKQNKR----LNLG----ATLNSLLF 706
                 |:....|...||:: ||.: ||..|.:     |..::.||    :::|    ..:|::..
Mosquito   767 FAPVWDRSRTLEGGQEQSDCGRRRTLRRGPKD-----PEARETKRIDRFMSIGKERSEEVNAMEA 826

  Fly   707 ----PEPFSSKA--TMAK----------ASLSQKP---KSVEE--------------------SE 732
                ||..|::.  |:||          ....|:|   ||.||                    ||
Mosquito   827 RPGQPEAASTREEFTIAKKEEVRLDSEEGQRQQEPVQEKSQEEPTIVSGENHDQVTDRTTMPPSE 891

  Fly   733 PE-----------EDVQPVPSARRRHSRLGHVANDFLQAQKELGKHFLSHINEHEHEFSLGDEGM 786
            .|           |:.|.||......|         |::..|.... :|.:..:.::.:|  :..
Mosquito   892 EEIHLYTPAPRTSEEQQSVPQLDPIWS---------LESSPESSAE-VSELMHNRYKRAL--QPS 944

  Fly   787 RESSLESANVGRKSLIQDHFEGKKATPTLHSKLPQKPADEGITSWWDLPAMRRRRAVLNTNSLAE 851
            .|:|:||..|.|   ::|.|.       .::||.||.|:                       :.:
Mosquito   945 AEASVESQEVQR---LEDFFR-------TNAKLQQKFAE-----------------------MFD 976

  Fly   852 LPSNAIDKADRDEMMPLGRYTYYEYKMDHEAEKDASQPRE--------EKESKIMRISSKNSLAS 908
            |...||::.|.:|      ....|...|.|||.|..:..|        .|.||      :|.|..
Mosquito   977 LLLEAIEELDAEE------NNAREMSDDGEAEHDGDEVAERAGTGMPSHKRSK------RNVLLH 1029

  Fly   909 GRSLTKLSESLVSTMKSKVSRFINIISNHM------NEWYNTLTKH---LETDAETQPPRRQNSI 964
            .:|......|.:...:.:...  :...||:      .....:|.:|   ::|..|:|.|..:...
Mosquito  1030 PQSWESRERSNMIHRRERSEE--DSYENHIIAAAQPKAPSKSLAEHAGGVQTSQESQQPEHEQDS 1092

  Fly   965 EK 966
            ::
Mosquito  1093 DE 1094