Protein Alignment CG7675 and DHRS12

DIOPT Version :9

• Sequence 1: NP_001287390.1
• Gene: CG7675 / 42211
• FlyBaseID: FBgn0038610
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_001364858.1
• Gene: DHRS12 / 79758
• HGNCID: 25832
• Length: 320
• Species: Homo sapiens
• Alignment Length: 213
• Identity: 67/213 - (31%)
• Similarity: 109/213 - (51%)
• Gaps: 15/213 - (7%)

  Fly    47 ETKMEGKTVIITGANSGIGKETAKDLAGRGARIIMACRNLETANAVKDEIVKETKNNKILVKKLD 111
            |.::.|:..::||.||||||.||.::|.||..:.:.||:...|...:.||::|:.|..|.:..:|
Human    35 EVQIPGRVFLVTGGNSGIGKATALEIAKRGGTVHLVCRDQAPAEDARGEIIRESGNQNIFLHIVD 99

  Fly   112 LGSQKSVREFAADIVKTEPKIDVLIHNAGMALAFRGQTSEDGVELTMATNHYGPFLLTHLLIDVL 176
            |...|.:.:|..:. |.|.|:.|||:||| .:..:.:.:|||:|...|.|..|.::||..||.||
Human   100 LSDPKQIWKFVENF-KQEHKLHVLINNAG-CMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVL 162

  Fly   177 KKSAPARIVIVASELYRLSSVNLAKLNPIGT-FPAAYLYYVSKFANIYFARELAKRLEGTKVTVN 240
            :|....|::.|:|....:..:|...|....| |....:|..:|...:.    |.:|.......::
Human   163 EKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVV----LTERWAQGHPAIH 223

  Fly   241 F--LHPGMIDSGIWRNVP 256
            |  :|||      |.:.|
Human   224 FSSMHPG------WADTP 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7675	NP_001287390.1	PRK06196	52..327	CDD:235736	66/208 (32%)
		retinol-DH_like_SDR_c_like	52..320	CDD:212492	66/208 (32%)
DHRS12	NP_001364858.1	NADB_Rossmann	40..>235	CDD:419666	65/206 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810