Protein Alignment CG7675 and Rdh12

DIOPT Version :10

• Sequence 1: NP_650717.1
• Gene: CG7675 / 42211
• FlyBaseID: FBgn0038610
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_084293.1
• Gene: Rdh12 / 77974
• MGIID: 1925224
• Length: 316
• Species: Mus musculus
• Alignment Length: 312
• Identity: 128/312 - (41%)
• Similarity: 198/312 - (63%)
• Gaps: 6/312 - (1%)

  Fly    17 IFLMTSVAAIV-ATLMSIRFYLRITAGRCFTETKMEGKTVIITGANSGIGKETAKDLAGRGARII 80
            :.|:||..:|: .|..|||.:  ...|.|.|..::.||.|:|||||:|||||||::||.||||:.
Mouse     5 LVLLTSFLSILYLTAPSIRKF--FAGGVCTTNVQIPGKVVVITGANTGIGKETARELARRGARVY 67

  Fly    81 MACRNLETANAVKDEIVKETKNNKILVKKLDLGSQKSVREFAADIVKTEPKIDVLIHNAGMALAF 145
            :|||::....:...||..:|||:::||:||||...||:|.||...:..|.|:.:||:|||:.:..
Mouse    68 IACRDVLKGESAASEIRADTKNSQVLVRKLDLSDTKSIRAFAERFLAEEKKLHILINNAGVMMCP 132

  Fly   146 RGQTSEDGVELTMATNHYGPFLLTHLLIDVLKKSAPARIVIVASELYRLSSVNLAKLNPIGTFPA 210
            ..:|: ||.|.....||.|.||||:||::.||:|||||:|.::|..:.:..:....|.....:.:
Mouse   133 YSKTT-DGFETHFGVNHLGHFLLTYLLLERLKESAPARVVNLSSIAHLIGKIRFHDLQGQKRYCS 196

  Fly   211 AYLYYVSKFANIYFARELAKRLEGTKVTVNFLHPGMIDSGIWRNVPFPLNLPMMAITKGFFKTTK 275
            |:.|..||.||:.|.|||||||:||.||...:|||::.|.|.|| .:.|.| :..:...|||:|.
Mouse   197 AFAYGHSKLANLLFTRELAKRLQGTGVTAYAVHPGVVLSEITRN-SYLLCL-LWRLFSPFFKSTS 259

  Fly   276 AGAQTTIYLATSNEVANVSGKYFMDCKEATLNAAALDEEKGLKIWEESVKIV 327
            .||||:::.|.:.::..:|||||.|||...:::.|.:::...::|..|.:::
Mouse   260 QGAQTSLHCALAEDLEPLSGKYFSDCKRMWVSSRARNKKTAERLWNVSCELL 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7675	NP_650717.1	retinol-DH_like_SDR_c_like	52..320	CDD:212492	115/267 (43%)
Rdh12	NP_084293.1	Rossmann-fold NAD(P)(+)-binding proteins	39..307	CDD:473865	116/270 (43%)