Protein Alignment CG7675 and DHRSX

DIOPT Version :10

• Sequence 1: NP_650717.1
• Gene: CG7675 / 42211
• FlyBaseID: FBgn0038610
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_660160.2
• Gene: DHRSX / 207063
• HGNCID: 18399
• Length: 330
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 90/280 - (32%)
• Similarity: 145/280 - (51%)
• Gaps: 7/280 - (2%)

  Fly    53 KTVIITGANSGIGKETAKDLAGRGARIIMACRNLETANAVKDEIVKETKNNKILVKKLDLGSQKS 117
            :..|:||...|||..|||.||..|..:|:|..|...|..|..:|.:||.|:|:.....||.|..|
Human    44 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCDLASMTS 108

  Fly   118 VREFAADIVKTEPKIDVLIHNAGMALAFRGQTSEDGVELTMATNHYGPFLLTHLLIDVLKKSA-- 180
            :|:|.......:..:.|||:|||:.:..:.:| .||.|.....|:.|.||||:||:|.||:|.
Human   109 IRQFVQKFKMKKIPLHVLINNAGVMMVPQRKT-RDGFEEHFGLNYLGHFLLTNLLLDTLKESGSP 172

  Fly   181 --PARIVIVASELYRLSSVNLAKLNPIGTFPAAYLYYVSKFANIYFARELAKRL--EGTKVTVNF 241
              .||:|.|:|..:.::.:|:..|.....:.....|..||.|.:.|...|.:.|  ||:.||.|.
Human   173 GHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFTYHLQRLLAAEGSHVTANV 237

  Fly   242 LHPGMIDSGIWRNVPFPLNLPMMAITKGFFKTTKAGAQTTIYLATSNEVANVSGKYFMDCKEATL 306
            :.||::::.::::|.:...|....:....|||...||.|:||.|.:.|:..|.|.|..:.||...
Human   238 VDPGVVNTDVYKHVFWATRLAKKLLGWLLFKTPDEGAWTSIYAAVTPELEGVGGHYLYNEKETKS 302

  Fly   307 NAAALDEEKGLKIWEESVKI 326
            .....:::...::|.:|.::
Human   303 LHVTYNQKLQQQLWSKSCEM 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7675	NP_650717.1	retinol-DH_like_SDR_c_like	52..320	CDD:212492	88/272 (32%)
DHRSX	NP_660160.2	retinol-DH_like_SDR_c_like	43..316	CDD:212492	88/272 (32%)