DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7675 and E04F6.15

DIOPT Version :9

Sequence 1:	NP_001287390.1	Gene:	CG7675 / 42211	FlyBaseID:	FBgn0038610	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_495501.1	Gene:	E04F6.15 / 184041	WormBaseID:	WBGene00017131	Length:	319	Species:	Caenorhabditis elegans

Alignment Length:	313	Identity:	105/313 - (33%)
Similarity:	155/313 - (49%)	Gaps:	28/313 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 RFYLRITAGRCFTETKMEGKTVIITGANSGIGKETAKDLAGRGARIIMACRNLETANAVKDEIVK 98
            :|:.|..|........:.|||..|||..||||.||||.|..:||.::|..||...:.|.|..::.
Worm    10 QFHSRTNALEVLDGIDLSGKTFAITGTTSGIGVETAKALILKGAHVVMINRNYTASEASKKSLLI 74

  Fly    99 ETKNNKILVKKLDLGSQKSVREFAADIVKTEPKIDVLIHNAGMALAFRGQTSEDGVELTMATNHY 163
            ||.|.:|.:.:.||.|..||::.|.:.::.:..:..||.|||: .....:|:.||.|.....||.
Worm    75 ETPNAQIDIVQCDLNSLSSVKKAADEYLEQKWPLHGLILNAGV-FGPSEKTTSDGFEAHFGINHL 138

  Fly   164 GPFLLTHLLIDVLKKSAPARIVIVASELYRLSSVN-----LAKLNPIGTFPAAY----LYYVSKF 219
            ..|:|...|:.||::|||:|||||.|.|.:.:.|.     :.||:.:....|..    ||..||.
Worm   139 AHFILIKELLPVLRESAPSRIVIVTSMLSKHTCVKPDSRIVEKLDTLCPKEATQWYFRLYAKSKM 203

  Fly   220 ANIYFARELAKRLEGTKVTVNFLHPGM-------IDSGIWRNVPFPLNLPMMAITKGFFKTTKAG 277
            .||..|.:|.:.....:::|..:|||.       .|.|:|....| |::|       |.|....|
Worm   204 CNILTAFKLHRDEFKNRISVYAVHPGSGVRTDLHRDFGLWSIADF-LSIP-------FTKNASQG 260

  Fly   278 AQTTIYLATSNEVANVSGKYFMDCKEATLN---AAALDEEKGLKIWEESVKIV 327
            |.|::|.|...||..:||||:..|.:...|   ..:.|||....:||.|.|::
Worm   261 AATSLYCAVHPEVKELSGKYWESCWDDEKNLDKKVSRDEELQEALWEHSEKLI 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7675	NP_001287390.1	PRK06196	52..327	CDD:235736	102/293 (35%)
CG7675	NP_001287390.1	retinol-DH_like_SDR_c_like	52..320	CDD:212492	98/286 (34%)
E04F6.15	NP_495501.1	PRK06196	11..312	CDD:235736	104/309 (34%)
E04F6.15	NP_495501.1	retinol-DH_like_SDR_c_like	28..306	CDD:212492	98/286 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.720