Protein Alignment CG7675 and Rdh11

DIOPT Version :10

• Sequence 1: NP_650717.1
• Gene: CG7675 / 42211
• FlyBaseID: FBgn0038610
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_067532.2
• Gene: Rdh11 / 17252
• MGIID: 102581
• Length: 316
• Species: Mus musculus
• Alignment Length: 316
• Identity: 120/316 - (37%)
• Similarity: 187/316 - (59%)
• Gaps: 4/316 - (1%)

  Fly    18 FLMTSVAAIVATLMSIRFYLRITAGRCFTETKMEGKTVIITGANSGIGKETAKDLAGRGARIIMA 82
            ||:......:..|::.:....:::|.|.:..::.||..|:||||:|||||||||||.||||:.:|
Mouse     4 FLLLLSLPFILYLVTPKIRKMLSSGVCTSNVQLPGKVAIVTGANTGIGKETAKDLAQRGARVYLA 68

  Fly    83 CRNLETANAVKDEIVKETKNNKILVKKLDLGSQKSVREFAADIVKTEPKIDVLIHNAGMALAFRG 147
            ||:::.......||...|.|:::.|:||||...||:|.||.|.:..|..:.:||:|||:.:....
Mouse    69 CRDVDKGELAAREIQAVTGNSQVFVRKLDLADTKSIRAFAKDFLAEEKHLHLLINNAGVMMCPYS 133

  Fly   148 QTSEDGVELTMATNHYGPFLLTHLLIDVLKKSAPARIVIVASELYRLSSVNLAKLNPIGTFPAAY 212
            :|: ||.|:.:..||.|.|||||||::.||:|||:|||.::|..:.|..::...|.....:.|..
Mouse   134 KTA-DGFEMHIGVNHLGHFLLTHLLLEKLKESAPSRIVNLSSLGHHLGRIHFHNLQGEKFYSAGL 197

  Fly   213 LYYVSKFANIYFARELAKRLEGTKVTVNFLHPGMIDSGIWRNVPFPLNLPMMAITKGFFKTTKAG 277
            .|..||.|||.|.:||||||:|:.||...:|||.:.|.:.|.......|..:...  |.||.:.|
Mouse   198 AYCHSKLANILFTKELAKRLKGSGVTTYSVHPGTVHSELTRYSSIMRWLWQLFFV--FIKTPQEG 260

  Fly   278 AQTTIYLATSNEVANVSGKYFMDCKEATLNAAALDEEKGLKIWEESVKIVKLTPQD 333
            |||::|.|.:..:.::||.:|.||:.|.::....:|....::|:.|..::.| |.|
Mouse   261 AQTSLYCALTEGLESLSGSHFSDCQLAWVSYQGRNEIIARRLWDVSCDLLGL-PVD 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7675	NP_650717.1	retinol-DH_like_SDR_c_like	52..320	CDD:212492	110/267 (41%)
Rdh11	NP_067532.2	Rossmann-fold NAD(P)(+)-binding proteins	38..306	CDD:473865	111/270 (41%)