Protein Alignment CG7675 and DHRS13

DIOPT Version :9

• Sequence 1: NP_001287390.1
• Gene: CG7675 / 42211
• FlyBaseID: FBgn0038610
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_653284.2
• Gene: DHRS13 / 147015
• HGNCID: 28326
• Length: 377
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 120/314 - (38%)
• Similarity: 182/314 - (57%)
• Gaps: 19/314 - (6%)

  Fly    35 FYLRITAGRCFTETKMEGKTVIITGANSGIGKETAKDLAGRGARIIMACRNLETANAVKDEIVKE 99
            :|..:.|..|.....:.|:|.::|||||||||.||.:||.||||:::|||:.|...|...::.:|
Human    19 YYNLVKAPPCGGMGNLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFDLRQE 83

  Fly   100 TKNNKILVKKLDLGSQKSVREFAADIVKTEPKIDVLIHNAGMALAFRGQTSEDGVELTMATNHYG 164
            :.||:::...|||.|..|||.||...:.:||::|:||||||::..  |:|.| ...|.:..||.|
Human    84 SGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSC--GRTRE-AFNLLLRVNHIG 145

  Fly   165 PFLLTHLLIDVLKKSAPARIVIVASELYRLSSVNLAKLN--PIGTFPAAYLYYVSKFANIYFARE 227
            ||||||||:..||..||:|:|:|||..:....::..:|:  .:|.......|..:|.||:.||||
Human   146 PFLLTHLLLPCLKACAPSRVVVVASAAHCRGRLDFKRLDRPVVGWRQELRAYADTKLANVLFARE 210

  Fly   228 LAKRLEGTKVTVNFLHPGMIDSGIW-RNVP---FPLNLPMMAITKGFFKTTKAGAQTTIYLATSN 288
            ||.:||.|.||....|||.::|.:: |:||   .||..|:..:.   .:..:.||||.:|.|...
Human   211 LANQLEATGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLV---LRAPRGGAQTPLYCALQE 272

  Fly   289 EVANVSGKYFMDCKEATLNAAALDEEKGLKIWEESVKIVKLTP-------QDPK 335
            .:..:||:||.:|....:..||.|:....::||.|.::..|.|       :||:
Human   273 GIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASKRLAGLGPGEDAEPDEDPQ 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7675	NP_001287390.1	PRK06196	52..327	CDD:235736	113/280 (40%)
		retinol-DH_like_SDR_c_like	52..320	CDD:212492	110/273 (40%)
DHRS13	NP_653284.2	retinol-DH_like_SDR_c_like	36..304	CDD:212492	110/273 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	309..377		4/18 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.690