DRSC/TRiP Functional Genomics Resources

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Protein Alignment gl and ZNF394

DIOPT Version :9

Sequence 1:NP_001262708.1 Gene:gl / 42210 FlyBaseID:FBgn0004618 Length:679 Species:Drosophila melanogaster
Sequence 2:NP_115540.2 Gene:ZNF394 / 84124 HGNCID:18832 Length:561 Species:Homo sapiens


Alignment Length:207 Identity:83/207 - (40%)
Similarity:109/207 - (52%) Gaps:47/207 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   394 PHKSPT--SYQAAALGLSLSAFEDEEDSNEDLDGDEGSSGGEMKPNLCRLCGKTYARPSTLKTHL 456
            ||||.:  |:..::|      ||.:...:|:            :|..|..|||::.:.|.|..|.
Human   331 PHKSDSGDSFHHSSL------FETQRQLHEE------------RPYKCGNCGKSFKQRSDLFRHQ 377

  Fly   457 RTHSGERPYRCPDCNKSFSQAANLTAHVRTHTGQKPFRCPICDRRFSQSSSVTTHMRTHS----- 516
            |.|:||:||.|.:|.|||||:|.||.|.|||||:||:.|..|..||.|:|.:..|..|||     
Human   378 RIHTGEKPYGCQECGKSFSQSAALTKHQRTHTGEKPYTCLKCGERFRQNSHLNRHQSTHSRDKHF 442

  Fly   517 ----------------------GERPYRCSSCKKSFSDSSTLTKHLRIHSGEKPYQCKLCLLRFS 559
                                  |||||:|..|:|||...|.|.||.|||:|||||.|.:|..||:
Human   443 KCEECGETCHISNLFRHQRLHKGERPYKCEECEKSFKQRSDLFKHHRIHTGEKPYGCSVCGKRFN 507

  Fly   560 QSGNLNRHMRVH 571
            ||..|.:|.|:|
Human   508 QSATLIKHQRIH 519

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
glNP_001262708.1 C2H2 Zn finger 439..459 CDD:275368 8/19 (42%)
zf-C2H2 439..459 CDD:278523 8/19 (42%)
zf-H2C2_2 452..476 CDD:290200 13/23 (57%)
C2H2 Zn finger 467..487 CDD:275368 12/19 (63%)
zf-H2C2_2 479..504 CDD:290200 14/24 (58%)
zf-C2H2_8 492..570 CDD:292531 41/104 (39%)
C2H2 Zn finger 495..515 CDD:275368 7/19 (37%)
zf-H2C2_2 507..531 CDD:290200 13/50 (26%)
C2H2 Zn finger 523..543 CDD:275368 10/19 (53%)
zf-H2C2_2 536..560 CDD:290200 15/23 (65%)
C2H2 Zn finger 551..571 CDD:275368 9/19 (47%)
ZNF394NP_115540.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..61
SCAN 60..170 CDD:128708
KRAB_A-box 155..214 CDD:322003
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 182..201
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 231..285
C2H2 Zn finger 337..353 CDD:275368 4/21 (19%)
COG5048 356..>420 CDD:227381 33/63 (52%)
C2H2 Zn finger 360..380 CDD:275368 8/19 (42%)
C2H2 Zn finger 388..408 CDD:275368 12/19 (63%)
zf-C2H2 414..436 CDD:306579 7/21 (33%)
C2H2 Zn finger 416..436 CDD:275368 7/19 (37%)
C2H2 Zn finger 444..463 CDD:275368 0/18 (0%)
SFP1 <464..543 CDD:227516 32/56 (57%)
C2H2 Zn finger 471..491 CDD:275368 10/19 (53%)
C2H2 Zn finger 499..519 CDD:275368 9/19 (47%)
C2H2 Zn finger 527..547 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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