DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment gl and STOP1

DIOPT Version :9

Sequence 1:	NP_001262708.1	Gene:	gl / 42210	FlyBaseID:	FBgn0004618	Length:	679	Species:	Drosophila melanogaster
Sequence 2:	NP_174697.1	Gene:	STOP1 / 840339	AraportID:	AT1G34370	Length:	499	Species:	Arabidopsis thaliana

Alignment Length:	563	Identity:	109/563 - (19%)
Similarity:	173/563 - (30%)	Gaps:	220/563 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 NNGAGGGSSGNHGYWSTDEMASTFPGLP-------------PLDIDPLPSLFPFSPCG------A 170
            |...|..||.:....|:|...|||.|..             .:.::|          |      |
plant     9 NTNWGSSSSKSREPGSSDCGNSTFAGFTSQQKWEDASILDYEMGVEP----------GLQESIQA 63

  Fly   171 SYNFAAGNPHQA-------ASLSY---TVHPHQMLISPNSHNHGQMHSQHQQHQHQQSQVQASHV 225
            :.:|..|...||       ::||:   .:|..|.|:.......||:..:..:...||.|:..:.:
plant    64 NVDFLQGVRAQAWDPRTMLSNLSFMEQKIHQLQDLVHLLVGRGGQLQGRQDELAAQQQQLITTDL 128

  Fly   226 GNSLLQSSGGNNIGSNGSAGGVANAASCYYETSAGTAAPPPP----PAAAMYPSMSVNVSMNMTM 286
            .:.::|.              ::.|.|.........:..|.|    |.:|::|.:.
plant   129 TSIIIQL--------------ISTAGSLLPSVKHNMSTAPGPFTGQPGSAVFPYVR--------- 170

  Fly   287 HHGYGAGDAGGVPMQCSQMNWTPPSNSTSAAAAAAAVNVLYPPLLSPGHYPASATYSFTADFRAP 351
                   :|..|..| ||.|     |:..|                             .:|..|
plant   171 -------EANNVASQ-SQNN-----NNCGA-----------------------------REFDLP 193

  Fly   352 APTGLGALPPLTVGEKESPSPPANSSLAGYYPTGVGNQGYTPPHKSPTSYQAAALGLSLSAFEDE 416
                    .|:.|.|:|.                                         ...|:.
plant   194 --------KPVLVDEREG-----------------------------------------HVVEEH 209

  Fly   417 EDSNEDLDGDEGSSGGEMKP------------------NLCRLCGKTYARPSTLKTHLRTHSGE- 462
            |..:|| |.:||.:   :.|                  :.|.:|||.:.|.:.|:.|:|.|..|
plant   210 EMKDED-DVEEGEN---LPPGSYEILQLEKEEILAPHTHFCTICGKGFKRDANLRMHMRGHGDEY 270

  Fly   463 ----------------------RPYRCP--DC-----NKSFSQAANLTA----HVRTHTGQKPFR 494
                                  :.|.||  .|     :|.|.....:..    :.|||. .|.|.
plant   271 KTAAALAKPNKESVPGSEPMLIKRYSCPFLGCKRNKEHKKFQPLKTILCVKNHYKRTHC-DKSFT 334

  Fly   495 CPIC-DRRFSQSSSVTTHMRTHSGERPYRCSSCKKSFSDSSTLTKHLRIHSGEKPYQCKLCLLRF 558
            |..| .::||..:.:.||.: |.|:..:.| ||..:||....|..|:.:..|..| ...|...:.
plant   335 CSRCHTKKFSVIADLKTHEK-HCGKNKWLC-SCGTTFSRKDKLFGHIALFQGHTP-AIPLEETKP 396

  Fly   559 SQSGNLNRHMRVHGNNNSSN-GSN-GATGVGGESSTGSGVGGG 599
            |.|.:..|.....||||... |.| |:.....:.:|..|:..|
plant   397 SASTSTQRGSSEGGNNNQGMVGFNLGSASNANQETTQPGMTDG 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gl	NP_001262708.1	C2H2 Zn finger	439..459	CDD:275368	8/19 (42%)
		zf-C2H2	439..459	CDD:278523	8/19 (42%)
		zf-H2C2_2	452..476	CDD:290200	11/53 (21%)
		C2H2 Zn finger	467..487	CDD:275368	6/30 (20%)
		zf-H2C2_2	479..504	CDD:290200	8/29 (28%)
		zf-C2H2_8	492..570	CDD:292531	22/78 (28%)
		C2H2 Zn finger	495..515	CDD:275368	6/20 (30%)
		zf-H2C2_2	507..531	CDD:290200	7/23 (30%)
		C2H2 Zn finger	523..543	CDD:275368	7/19 (37%)
		zf-H2C2_2	536..560	CDD:290200	5/23 (22%)
		C2H2 Zn finger	551..571	CDD:275368	4/19 (21%)
STOP1	NP_174697.1	zf-C2H2	244..266	CDD:333835	8/21 (38%)
		C2H2 Zn finger	246..266	CDD:275368	8/19 (42%)
		C2H2 Zn finger	297..328	CDD:275368	6/30 (20%)
		C2H2 Zn finger	335..354	CDD:275368	6/18 (33%)
		C2H2 Zn finger	363..379	CDD:275370	6/16 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000