DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gl and LOC799968

DIOPT Version :9

Sequence 1:	NP_001262708.1	Gene:	gl / 42210	FlyBaseID:	FBgn0004618	Length:	679	Species:	Drosophila melanogaster
Sequence 2:	XP_001340263.4	Gene:	LOC799968 / 799968	-ID:	-	Length:	886	Species:	Danio rerio

Alignment Length:	727	Identity:	148/727 - (20%)
Similarity:	236/727 - (32%)	Gaps:	264/727 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 QGSTALPISSLTSSDFDCGGCFDPTIGVGVGIGGGHIQISTTPPASSGNGSSNNGAGGGSSGNH- 136
            :|.:..|::.| ||:.....|             ||....:|.|....:.|:.....|.||.|.
Zfish   196 RGKSPPPVTPL-SSNLSVTSC-------------GHKPNQSTQPIQGTSLSTKENREGLSSQNKK 246

  Fly   137 ------GYWSTDEMA-STFP--------GLPPLDIDPLPSLFPFSPCGAS--YNFAAGNPHQAAS 184
                  ...||..:. |:.|        .:|.:.:...||: |.:....|  :...:.|||.:
Zfish   247 QDASVPAQTSTTSVPNSSIPARTACAKLSVPMIQLSGAPSI-PQAKQSTSLVHRRPSPNPHAS-- 308

  Fly   185 LSYTV----------HPHQ------------MLISPNSH------NHGQMHSQHQQHQHQQSQ-- 219
             :.||          ||.|            ::..|.|:      .|.:..:......:|.:|
Zfish   309 -NQTVVPQKEESDMCHPLQNTILSAVPSSQVVVAEPTSNKQRALFTHTEKSASSITSINQATQTF 372

  Fly   220 ------------VQASHVGNSLLQSSGGNNIGSNGSAGGVANAAS---CYYETSAGTAAPPPPPA 269
                        :|...:.|   |:.....:.......|:..|.|   .......||...||.|.
Zfish   373 AQCSAKLTQPPFIQPQAIKN---QAQEMTPVVHTAMPSGLVPATSSKPTQVHDRRGTNLVPPRPH 434

  Fly   270 AAMYPSMSVNVSMNMTMHHGYGAGDAGG-------VPMQCSQMNWTPPSNSTSAA-------AAA 320
            |...|.:       :..|.|..:..:..       ||......::.|...|.|::       .|:
Zfish   435 AFASPQV-------IPAHSGAHSNPSFSFPAVQPVVPTPAKPTSYLPMLVSFSSSHLPVNTIPAS 492

  Fly   321 AAVNVLYPPLLSPGHYPASATYSFTADFRAPAPTG----------LGALPPLTVGEKESP--SPP 373
            .::|...|.|....:.|.|..:|.::....|.|..          |...||:.:..:::|  :||
Zfish   493 PSLNPPQPSLTQSQYPPQSDQFSSSSSQFCPLPDNSPDLLESLDCLHLQPPIMITPQDAPDQAPP 557

  Fly   374 ANSSLAGYYPTGVGNQGYTPPHKSPTSYQAAALGLSL-------------------------SAF 413
            .:..         .:.|...|..:|...||||...::                         ...
Zfish   558 HHFQ---------SSSGQLAPLLTPKEQQAAAASANVVLGRVPARSLQTSVPLVENLPFSPHCRA 613

  Fly   414 EDEEDSNEDLDGDE---------------------------------------------GSSGG- 432
            |..:.:||||..|:                                             ||:.|
Zfish   614 ETTDRNNEDLSDDDTPTLQSRLRKQRKLCFNSRQVDPSVKEGMIKDQLQNDLTRESQLSGSNNGC 678

  Fly   433 EMKPNL----------CRLCGKTYARPSTLKTHLRTHSGERPYRCPDCNKSFSQA---------- 477
            :..|.|          |..||:..:..|.|:.|:|.|:|||||.|..|.|:|...
Zfish   679 QTLPKLLGKTLQRNTECPDCGRILSNASALENHMRLHTGERPYTCSQCGKAFPSVRGLNRHMKVH 743

  Fly   478 ----------------------------------------------ANLTAHVRTHTGQKPFRCP 496
                                                          |:.:.|:|.|||:|||.|.
Zfish   744 AEEKRYQCEECGKSFVYHFTLTKHQLIHSGERPFPCKVCGKRFLAKADRSTHMRMHTGEKPFSCT 808

  Fly   497 ICDRRFSQSSSVTTHMRTHSGERPYRCSSCKKSFSDSSTLTKHLRIHSGEKPYQCKLCLLRFSQS 561
            :|.:||....::..||:.|.||:.|.|..|:|.|.|.....:|..||:||:|::||.|..||:||
Zfish   809 LCGKRFKHRVALNMHMQGHRGEKRYTCPHCEKGFVDLGNFKRHKLIHTGERPFECKECGKRFTQS 873

  Fly   562 GNLNRHMRV-HG 572
            .:|.:|:.. ||
Zfish   874 AHLKKHLHTQHG 885

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gl	NP_001262708.1	C2H2 Zn finger	439..459	CDD:275368	7/19 (37%)
		zf-C2H2	439..459	CDD:278523	7/19 (37%)
		zf-H2C2_2	452..476	CDD:290200	13/23 (57%)
		C2H2 Zn finger	467..487	CDD:275368	7/75 (9%)
		zf-H2C2_2	479..504	CDD:290200	12/24 (50%)
		zf-C2H2_8	492..570	CDD:292531	32/77 (42%)
		C2H2 Zn finger	495..515	CDD:275368	6/19 (32%)
		zf-H2C2_2	507..531	CDD:290200	9/23 (39%)
		C2H2 Zn finger	523..543	CDD:275368	6/19 (32%)
		zf-H2C2_2	536..560	CDD:290200	11/23 (48%)
		C2H2 Zn finger	551..571	CDD:275368	9/20 (45%)
LOC799968	XP_001340263.4	C2H2 Zn finger	695..715	CDD:275368	7/19 (37%)
		zf-H2C2_2	707..730	CDD:290200	12/22 (55%)
		C2H2 Zn finger	723..743	CDD:275368	4/19 (21%)
		zf-H2C2_2	736..760	CDD:290200	0/23 (0%)
		C2H2 Zn finger	751..771	CDD:275368	0/19 (0%)
		zf-H2C2_2	764..786	CDD:290200	0/21 (0%)
		C2H2 Zn finger	779..799	CDD:275368	3/19 (16%)
		zf-H2C2_2	791..816	CDD:290200	12/24 (50%)
		C2H2 Zn finger	807..827	CDD:275368	6/19 (32%)
		zf-H2C2_2	819..843	CDD:290200	9/23 (39%)
		C2H2 Zn finger	835..855	CDD:275368	6/19 (32%)
		zf-H2C2_2	847..872	CDD:290200	11/24 (46%)
		C2H2 Zn finger	863..882	CDD:275368	9/18 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2374
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.030