DRSC/TRiP Functional Genomics Resources

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Protein Alignment gl and Fezf2

DIOPT Version :10

Sequence 1:NP_001262708.1 Gene:gl / 42210 FlyBaseID:FBgn0004618 Length:679 Species:Drosophila melanogaster
Sequence 2:NP_536681.2 Gene:Fezf2 / 54713 MGIID:1859823 Length:455 Species:Mus musculus


Alignment Length:438 Identity:123/438 - (28%)
Similarity:167/438 - (38%) Gaps:120/438 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   158 PLPSLFPFSPCGASYNFAAGNPHQAASLSYTVHPHQMLISPNSHNHGQMHSQHQQHQHQQSQVQA 222
            |||.:.|..|.|                 |.| |.:.|:|                        .
Mouse    69 PLPCMIPLQPLG-----------------YEV-PSKTLLS------------------------Y 91

  Fly   223 SHVGNSLLQSSGGNNIGSNGSAGGV-ANAASCYYETSAGTA-------APPPPPAAAMYPSMSVN 279
            |....|.|::.||   |..||.||. ...||...:|:.|..       ||...||..:.....:|
Mouse    92 SEFWKSSLRAGGG---GGGGSGGGAPVCGASGLCKTNCGVCCKAELGLAPSALPAGRVIKPQVIN 153

  Fly   280 VSMNMTMHHGYGAGDAGGVPMQCS--QMNWTPPSNSTSAAAAAAAVNVLYPPL-LSPGH-YPASA 340
                          .|.|:|...|  ..|:.   :||:           |||. |..|| :|:..
Mouse   154 --------------QAVGLPASGSLYYFNYL---DSTA-----------YPPSELLGGHLFPSGL 190

  Fly   341 TYSFTADFRAPAPTGLGALPPLTVGEKESPSPPANSSLAGY------YPTGVGNQGYTPPHK--- 396
                   ..|.|||.|.|.|.|.:.|        |:.||..      :|...       |||   
Mouse   191 -------LNAQAPTSLAAHPKLFLLE--------NAKLASLAADKFPHPASY-------PHKERL 233

  Fly   397 -SPTSYQAAALGLSLSAFEDEEDSNEDLDGDEGSSGGEMKPNLCRLCGKTYARPSTLKTHLRTHS 460
             :|.. |......:|:|......|:..|.|  ||:..:.|...|.:|||.:.....|..|:..|:
Mouse   234 HAPLE-QVLKENSALTAERGGVKSHSKLPG--GSTDSKPKNFTCEVCGKVFNAHYNLTRHMPVHT 295

  Fly   461 GERPYRCPDCNKSFSQAANLTAHVRTHTGQKPFRCPICDRRFSQSSSVTTHMRTHSGERPYRCSS 525
            |.||:.|..|.|.|.||:.|..|...||.:||.:|..|.:.|::||::.||:|.|:|.:|:.|..
Mouse   296 GARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHIRIHAGYKPFVCEF 360

  Fly   526 CKKSFSDSSTLTKHLRIHSGEKPYQCKLCLLRFSQSGNLNRHMRVHGN 573
            |.|.|........|...|||||.|:|.:|...|.|..||..||..|.:
Mouse   361 CGKGFHQKGNYKNHKLTHSGEKQYKCTICNKAFHQVYNLTFHMHTHND 408

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
glNP_001262708.1 COG5048 <426..571 CDD:227381 55/144 (38%)
C2H2 Zn finger 439..459 CDD:275368 6/19 (32%)
C2H2 Zn finger 467..487 CDD:275368 8/19 (42%)
C2H2 Zn finger 495..515 CDD:275368 8/19 (42%)
C2H2 Zn finger 523..543 CDD:275368 5/19 (26%)
C2H2 Zn finger 551..571 CDD:275368 8/19 (42%)
Fezf2NP_536681.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..22
Engrailed homology 1 repressor 27..42
C2H2 Zn finger 274..294 CDD:275368 6/19 (32%)
COG5048 <284..>390 CDD:227381 41/105 (39%)
C2H2 Zn finger 302..322 CDD:275368 8/19 (42%)
zf-H2C2_2 317..339 CDD:463886 8/21 (38%)
C2H2 Zn finger 330..350 CDD:275368 8/19 (42%)
C2H2 Zn finger 358..378 CDD:275368 5/19 (26%)
SFP1 <380..436 CDD:227516 13/29 (45%)
C2H2 Zn finger 386..406 CDD:275368 8/19 (42%)
C2H2 Zn finger 414..432 CDD:275368
Blue background indicates that the domain is not in the aligned region.

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