DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment gl and Zfp72

DIOPT Version :9

Sequence 1:	NP_001262708.1	Gene:	gl / 42210	FlyBaseID:	FBgn0004618	Length:	679	Species:	Drosophila melanogaster
Sequence 2:	NP_001360967.1	Gene:	Zfp72 / 238722	MGIID:	3033356	Length:	489	Species:	Mus musculus

Alignment Length:	177	Identity:	74/177 - (41%)
Similarity:	104/177 - (58%)	Gaps:	9/177 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   395 HKSPTSYQAAALGLSLSAFEDEEDSNEDLDGDEGSSGGEMKPNLCRLCGKTYARPSTLKTHLRTH 459
            |.....|:....|||.:.        ..|...:....|| |...|..|||.:...|.|..|...|
Mouse   208 HSGEKPYKCEECGLSFNC--------SHLYRHQRIHTGE-KLYKCEECGKAFNCSSYLNYHQILH 263

  Fly   460 SGERPYRCPDCNKSFSQAANLTAHVRTHTGQKPFRCPICDRRFSQSSSVTTHMRTHSGERPYRCS 524
            :|::||:|.:|.|:|:..:.||.|.|.|||:||::|..||:.||..|::..|.|.|:||:||:||
Mouse   264 TGDKPYKCRECGKAFTMVSYLTRHQRIHTGEKPYKCKECDKAFSNCSALIQHQRIHTGEKPYKCS 328

  Fly   525 SCKKSFSDSSTLTKHLRIHSGEKPYQCKLCLLRFSQSGNLNRHMRVH 571
            .|.|:|::||:||.|.|||:|||||:||.|...|:.|.:||.|.|:|
Mouse   329 ECGKAFNNSSSLTHHQRIHTGEKPYECKECGKAFNSSSHLNYHHRIH 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gl	NP_001262708.1	C2H2 Zn finger	439..459	CDD:275368	7/19 (37%)
		zf-C2H2	439..459	CDD:278523	7/19 (37%)
		zf-H2C2_2	452..476	CDD:290200	10/23 (43%)
		C2H2 Zn finger	467..487	CDD:275368	8/19 (42%)
		zf-H2C2_2	479..504	CDD:290200	13/24 (54%)
		zf-C2H2_8	492..570	CDD:292531	40/77 (52%)
		C2H2 Zn finger	495..515	CDD:275368	8/19 (42%)
		zf-H2C2_2	507..531	CDD:290200	11/23 (48%)
		C2H2 Zn finger	523..543	CDD:275368	11/19 (58%)
		zf-H2C2_2	536..560	CDD:290200	15/23 (65%)
		C2H2 Zn finger	551..571	CDD:275368	9/19 (47%)
Zfp72	NP_001360967.1	KRAB	26..85	CDD:214630
		COG5048	99..472	CDD:227381	74/177 (42%)
		C2H2 Zn finger	105..124	CDD:275368
		C2H2 Zn finger	132..152	CDD:275368
		C2H2 Zn finger	160..180	CDD:275368
		C2H2 Zn finger	188..208	CDD:275368	74/177 (42%)
		C2H2 Zn finger	216..235	CDD:275368	4/26 (15%)
		C2H2 Zn finger	243..263	CDD:275368	7/19 (37%)
		C2H2 Zn finger	271..291	CDD:275368	8/19 (42%)
		C2H2 Zn finger	299..319	CDD:275368	8/19 (42%)
		C2H2 Zn finger	327..347	CDD:275368	11/19 (58%)
		C2H2 Zn finger	355..375	CDD:275368	9/19 (47%)
		C2H2 Zn finger	383..403	CDD:275368
		C2H2 Zn finger	411..431	CDD:275368
		C2H2 Zn finger	439..459	CDD:275368
		C2H2 Zn finger	467..487	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910