DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gl and Vezf1

DIOPT Version :9

Sequence 1:	NP_001262708.1	Gene:	gl / 42210	FlyBaseID:	FBgn0004618	Length:	679	Species:	Drosophila melanogaster
Sequence 2:	XP_036012519.1	Gene:	Vezf1 / 22344	MGIID:	1313291	Length:	556	Species:	Mus musculus

Alignment Length:	243	Identity:	64/243 - (26%)
Similarity:	106/243 - (43%)	Gaps:	42/243 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   367 KESPSP--PANSSLAGYYPTGVGNQGYTPPHKSPTSYQAAALGLSLSAFEDEEDSNEDLDGDEGS 429
            |::|:.  |..|::||              ..|.||..:...|:..:.......:|........|
Mouse   138 KKTPTTVVPLISTIAG--------------DSSRTSLVSTIAGILSTVTTSSSGTNPSSSASTTS 188

  Fly   430 ----------SGGEMKPNLCRLCGKTYARPSTLKTHLRTHSGERPYRCPDCNKSFSQAANLTAHV 484
                      |....|.:.|.:|||.:.....|..|..:||.|:|:.||.||:.|.:...:|.||
Mouse   189 MPVPQSVKKPSKPVKKNHACEMCGKAFRDVYHLNRHKLSHSDEKPFECPICNQRFKRKDRMTYHV 253

  Fly   485 RTHTG--QKPFRCPICDRRFSQSSSVTTHMR-THSGERPYRC------SSCKKSFSDSSTLTKHL 540
            |:|.|  .||:.|.:|.:.||:...::.|:: .||.|||::|      .:|..:|:....|..|:
Mouse   254 RSHEGGITKPYTCSVCGKGFSRPDHLSCHVKHVHSTERPFKCQFSSLMQTCTAAFATKDRLRTHM 318

  Fly   541 RIHSGEKPYQCKLC--LLRFSQSGNLNRHMRVHGNNNSSNGSNGATGV 586
            ..|.|:  ..|.:|  ||   .:..:..|::.||.:.|.|.:....|:
Mouse   319 VRHEGK--VSCNICGKLL---SAAYITSHLKTHGQSQSINCNTCKQGI 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gl	NP_001262708.1	C2H2 Zn finger	439..459	CDD:275368	6/19 (32%)
		zf-C2H2	439..459	CDD:278523	6/19 (32%)
		zf-H2C2_2	452..476	CDD:290200	11/23 (48%)
		C2H2 Zn finger	467..487	CDD:275368	9/19 (47%)
		zf-H2C2_2	479..504	CDD:290200	11/26 (42%)
		zf-C2H2_8	492..570	CDD:292531	23/86 (27%)
		C2H2 Zn finger	495..515	CDD:275368	5/20 (25%)
		zf-H2C2_2	507..531	CDD:290200	8/30 (27%)
		C2H2 Zn finger	523..543	CDD:275368	5/25 (20%)
		zf-H2C2_2	536..560	CDD:290200	8/25 (32%)
		C2H2 Zn finger	551..571	CDD:275368	5/21 (24%)
Vezf1	XP_036012519.1	zf-C2H2	106..125	CDD:395048
		C2H2 Zn finger	108..128	CDD:275368
		zf-C2H2	206..228	CDD:395048	6/21 (29%)
		C2H2 Zn finger	208..228	CDD:275368	6/19 (32%)
		SFP1	<230..287	CDD:227516	20/56 (36%)
		C2H2 Zn finger	236..256	CDD:275368	9/19 (47%)
		C2H2 Zn finger	266..284	CDD:275368	5/17 (29%)
		C2H2 Zn finger	295..321	CDD:275368	5/25 (20%)
		motB	<415..532	CDD:183756
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3992
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950