DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gl and che-1

DIOPT Version :9

Sequence 1:	NP_001262708.1	Gene:	gl / 42210	FlyBaseID:	FBgn0004618	Length:	679	Species:	Drosophila melanogaster
Sequence 2:	NP_001076598.1	Gene:	che-1 / 183847	WormBaseID:	WBGene00000483	Length:	273	Species:	Caenorhabditis elegans

Alignment Length:	342	Identity:	110/342 - (32%)
Similarity:	142/342 - (41%)	Gaps:	133/342 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   277 SVNVSMNMTMHHGYG---AGD------AGGVPMQCSQM-----------------------NWTP 309
            |.|....|.|||||.   |.|      :.|...|..|.                       :|
Worm    17 SANYIPQMQMHHGYQDFYASDSTSSMPSSGTTQQALQQTENGIIQGQNGSDHGAYGGWRQHDW-- 79

  Fly   310 PSNSTSAAAAAAAVNVLYPPL-LSPG----------HYPASATYSFTADFRAPAPTGLGALPPLT 363
              ||||:.:....:.:....| :|.|          ....::.:..|..||...|:||..:.|
Worm    80 --NSTSSWSIGNQLEMENGTLTMSHGATNDGNIRNNQQMMTSNHITTDSFRQIPPSGLCYMDP-- 140

  Fly   364 VGEKESPSPPANSSLAGYYPTGVGNQGYTP----PHKSPTSYQAAALGLSLSAFEDEEDSNEDLD 424
                                        ||    |.|.|...|
Worm   141 ----------------------------TPSLRLPKKEPLPVQ---------------------- 155

  Fly   425 GDEGSSGGEMKPNLCRLCGKTYARPSTLKTHLRTHSGERPYRCPDCNKSFSQAANLTAHVRTHTG 489
                                   ||....|       .:|:||..|.|:||||||||||.|.|||
Worm   156 -----------------------RPMARST-------PKPFRCQTCGKAFSQAANLTAHKRIHTG 190

  Fly   490 QKPFRCPICDRRFSQSSSVTTHMRTHSGERPYRCSSCKKSFSDSSTLTKHLRIHSGEKPYQCKLC 554
            :|||.||:|:|.||||||:.||.|||:|||||.|:.|:|:|:||||||||||.|:|.|||.|.:|
Worm   191 EKPFMCPVCNRPFSQSSSLVTHRRTHTGERPYPCAQCEKAFTDSSTLTKHLRTHTGHKPYVCSIC 255

  Fly   555 LLRFSQSGNLNRHMRVH 571
            :::|:|||||:|||:.|
Worm   256 MMKFTQSGNLHRHMKTH 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gl	NP_001262708.1	C2H2 Zn finger	439..459	CDD:275368	3/19 (16%)
		zf-C2H2	439..459	CDD:278523	3/19 (16%)
		zf-H2C2_2	452..476	CDD:290200	7/23 (30%)
		C2H2 Zn finger	467..487	CDD:275368	14/19 (74%)
		zf-H2C2_2	479..504	CDD:290200	17/24 (71%)
		zf-C2H2_8	492..570	CDD:292531	52/77 (68%)
		C2H2 Zn finger	495..515	CDD:275368	13/19 (68%)
		zf-H2C2_2	507..531	CDD:290200	14/23 (61%)
		C2H2 Zn finger	523..543	CDD:275368	14/19 (74%)
		zf-H2C2_2	536..560	CDD:290200	14/23 (61%)
		C2H2 Zn finger	551..571	CDD:275368	11/19 (58%)
che-1	NP_001076598.1	zf-C2H2	166..188	CDD:278523	15/21 (71%)
		C2H2 Zn finger	168..188	CDD:275368	14/19 (74%)
		zf-H2C2_2	180..205	CDD:290200	17/24 (71%)
		C2H2 Zn finger	196..216	CDD:275368	13/19 (68%)
		zf-H2C2_2	208..232	CDD:290200	14/23 (61%)
		C2H2 Zn finger	224..244	CDD:275368	14/19 (74%)
		zf-H2C2_2	237..261	CDD:290200	14/23 (61%)
		C2H2 Zn finger	252..272	CDD:275368	11/19 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto20796
orthoMCL	1	0.900	-	-		OOG6_110492
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2374
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840