Protein Alignment WRNexo and Exd2

DIOPT Version :9

• Sequence 1: NP_001163646.1
• Gene: WRNexo / 42208
• FlyBaseID: FBgn0038608
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_598559.2
• Gene: Exd2 / 97827
• MGIID: 1922485
• Length: 650
• Species: Mus musculus
• Alignment Length: 329
• Identity: 64/329 - (19%)
• Similarity: 125/329 - (37%)
• Gaps: 87/329 - (26%)

  Fly    79 KTEKLAMEE-ENPPKRRSSRLTRSTRSMAEDGSPSPEKEKP----------EKLPFIKYKGAIK- 131
            ||.::..:: :.|.:.:..:.....:...:...|.|:::.|          ::|||    ||::
Mouse    34 KTSRVMQQQPQQPQQPQQPQPQPQPQPQPQPEHPQPQQQVPGGREWPPPEDDQLPF----GALRA 94

  Fly   132 -------------YFTESQDIAASADDVLQWVEKQKDEVVPMAFDMEWPFSFQTGPGKSAVIQIC 183
                         ..|.||:  |..:.:..:::::.::...:..|.|| .:.:......:::|:.
Mouse    95 PRASWEERILQAEVVTVSQE--AEWNQIQPFLKRELEDFPVLGIDCEW-VNLEGKASPLSLLQMA 156

  Fly   184 VDEKCCYIYQLTNV----KKLPAALVALINHPKVRLHGVNIKNDFRKLARDFPEVTAEPLIEKCV 244
            .....|.:.:|..:    :.||..|:.::....:...||....|..||.:|:..:     :..|:
Mouse   157 SPSGFCALVRLPRLIYGGRTLPRTLLDILADGAILKVGVGCSEDANKLLQDYGLI-----VRGCL 216

  Fly   245 DL---------GLWCNEVCETGGRWSLERLTNFIAKKAMDKSKKVRMSKWHVIPLDENQLMYAAI 300
            ||         .:.||.:       ||:.|...|....:|||..:|.|.|....|.|:|:.|||.
Mouse   217 DLRYLAMKQGNNILCNGL-------SLKSLAETILNFPLDKSLLLRCSNWDAENLTEDQVTYAAR 274

  Fly   301 DVYIGQVIY------------------------RELER-REKVKIKNEEE-----FKEKNGDAAF 335
            |..|...::                        :.||| |..|.|....:     .:|.||:|..
Mouse   275 DAQISVALFLHLLGYPFSRDSYEEESTDQINWQKALERCRNMVDIPFRSKGLGRLVEEVNGEALE 339

  Fly   336 KAMK 339
            ..:|
Mouse   340 SQLK 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WRNexo	NP_001163646.1	WRN_exo	142..314	CDD:176653	39/208 (19%)
Exd2	NP_598559.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	34..89		7/54 (13%)
		WRN_exo	111..287	CDD:176653	41/190 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	340..373		1/4 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4373
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13620
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910