Sequence 1: | NP_001163646.1 | Gene: | WRNexo / 42208 | FlyBaseID: | FBgn0038608 | Length: | 354 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_000544.2 | Gene: | WRN / 7486 | HGNCID: | 12791 | Length: | 1432 | Species: | Homo sapiens |
Alignment Length: | 267 | Identity: | 85/267 - (31%) |
---|---|---|---|
Similarity: | 132/267 - (49%) | Gaps: | 40/267 - (14%) |
- Green bases have known domain annotations that are detailed below.
Fly 67 AAKRKNLDTPDVKTEKLAMEEENPPKRRSSRLTRSTRSMAEDGSPSPEKEKPEKLPFIKYKGAIK 131
Fly 132 YFTESQDIAASADDVLQWVEKQKDEVVPMAFDMEWPFSFQTGP-GKSAVIQICVDEKCCYIYQLT 195
Fly 196 NVKKLPAALVALINHPKVRLHGVNIKNDFRKLARDFPEVTAEPLIEKCVDLG---LWCNEVCETG 257
Fly 258 GRWSLERLTNFIAKKAMDKSKKVRMSKWHVIPLDENQLMYAAIDVYIGQVIYRELE----RREKV 318
Fly 319 KIKNEEE 325 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
WRNexo | NP_001163646.1 | WRN_exo | 142..314 | CDD:176653 | 63/179 (35%) |
WRN | NP_000544.2 | Interaction with WRNIP1. /evidence=ECO:0000250 | 2..277 | 85/267 (32%) | |
RNaseD_like | 61..229 | CDD:176650 | 63/179 (35%) | ||
2 X 27 AA tandem repeats of H-L-S-P-N-D-N-E-N-D-T-S-Y-V-I-E-S-D-E-D-L-E-M-E-M-L-K | 424..477 | ||||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 498..529 | ||||
recQ_fam | 538..1010 | CDD:129701 | |||
DEAD | 551..712 | CDD:278688 | |||
DEAH box | 668..671 | ||||
HELICc | 759..867 | CDD:238034 | |||
RecQ_Zn_bind | 872..939 | CDD:292742 | |||
RQC | 958..1051 | CDD:214936 | |||
Interaction with DNA. /evidence=ECO:0000269|PubMed:20159463 | 987..993 | ||||
HRDC | 1156..1229 | CDD:128635 | |||
HTH_40 | 1261..1351 | CDD:291179 | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 1 | 1.000 | 104 | 1.000 | Domainoid score | I6735 |
eggNOG | 1 | 0.900 | - | - | E1_KOG4373 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S4207 |
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
4 | 3.760 |