Protein Alignment WRNexo and Exd2

DIOPT Version :10

• Sequence 1: NP_001163646.1
• Gene: WRNexo / 42208
• FlyBaseID: FBgn0038608
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_001420937.1
• Gene: Exd2 / 362759
• RGDID: 1311087
• Length: 648
• Species: Rattus norvegicus
• Alignment Length: 315
• Identity: 66/315 - (20%)
• Similarity: 120/315 - (38%)
• Gaps: 79/315 - (25%)

  Fly    76 PDVKTEKLAMEEENPPKRRSSRLTRSTRSMAEDGS---PSPEKEKPEKLPFIKYKGAIK------ 131
            |..:.:....:::.||::...:       ....|:   |.||   .::|||    ||::
  Rat    47 PQQQQQPQPQQQQQPPQQEQQK-------QQVPGAREWPPPE---DDQLPF----GALRTPRASW 97

  Fly   132 --------YFTESQDIAASADDVLQWVEKQKDEVVPMAFDMEWPFSFQTGPGKSAVIQICVDEKC 188
                    ..|.||:  |..:.:..:::::.::...:..|.|| .:.:......:::|:......
  Rat    98 EERILQAEVVTVSQE--AEWNQIQPFLKRELEDFPVLGIDCEW-VNLEGKASPLSLLQMASPSGF 159

  Fly   189 CYIYQLTNV----KKLPAALVALINHPKVRLHGVNIKNDFRKLARDFPEVTAEPLIEKCVDL--- 246
            |.:.:|..:    |.||..|:.::....:...||....|..||.:|:..:     :..|:||
  Rat   160 CALVRLPRLIYGGKTLPRTLLDILADGTILKVGVGCSEDANKLLQDYGLI-----VRGCLDLRYL 219

  Fly   247 ------GLWCNEVCETGGRWSLERLTNFIAKKAMDKSKKVRMSKWHVIPLDENQLMYAAIDVYIG 305
                  .:.||.:       ||:.|...:....:|||..:|.|.|....|.|:|:.|||.|..|.
  Rat   220 AMKQGNSVLCNGL-------SLKSLAETLLNFPLDKSLLLRCSNWDAENLTEDQVTYAARDAQIS 277

  Fly   306 QVIYRELERREKVKIKNEEEFKEKNG---------------DAAF--KAMKALGE 343
            ..::..|......:...||   |.||               |..|  |.:..|||
  Rat   278 VALFLHLLGYPFSRNSYEE---ENNGQINWQKVLEKCRDMVDIPFRSKGLARLGE 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WRNexo	NP_001163646.1	PLN02967	16..>114	CDD:215521	5/40 (13%)
		WRN_exo	142..314	CDD:176653	39/184 (21%)
Exd2	NP_001420937.1	WRN_exo	109..285	CDD:176653	41/190 (22%)