Protein Alignment CG15803 and lnx2

DIOPT Version :10

• Sequence 1: NP_001287388.1
• Gene: CG15803 / 42206
• FlyBaseID: FBgn0038606
• Length: 880
• Species: Drosophila melanogaster
• Sequence 2: NP_001072606.1
• Gene: lnx2 / 780062
• XenbaseID: XB-GENE-877144
• Length: 685
• Species: Xenopus tropicalis
• Alignment Length: 691
• Identity: 133/691 - (19%)
• Similarity: 231/691 - (33%)
• Gaps: 193/691 - (27%)

  Fly    36 IKALTPGGVAERDGRLQLGDHLLQIGEVNLRGFSSEQVATVLRQTGAQVRLIVARPVEPTAIDYQ 100
            :|...||....|:   .|..|.....::.:.|   |..:.::...|         ||.|.: |..
 Frog   131 LKNRCPGASHRRE---LLNQHRASKLQIEIEG---ENGSVLIDHQG---------PVSPES-DKT 179

  Fly   101 TLACQAP---IIPTKLLSDPEELSRHLFQNPSFATAAVAAAAAAAAAAGSGSDGDVGGGGVLDVA 162
            ......|   :.|:.:   |..:..|.|.||:|..:.||.|.....:...|.            .
 Frog   180 RSGSALPERNVTPSVM---PAWMEEHGFDNPAFEESTVADATHPPPSLPEGE------------I 229

  Fly   163 SLVGLVRGGPAEGTELSAVEPQPSAAV-LQLQQLSE----------LAGD----LADFPLPPIPG 212
            :.:.:.|..|.....:|.|....:..: :.:|::..          ||||    :.:|.:
 Frog   230 TTIEIHRSNPYIELGISIVGGNETPLINVVIQEIYRDGVIARDGRLLAGDQILQVNNFDI----- 289

  Fly   213 GGGHSMVTDSNAG---QRPCPRLDLDIVPFSILSPPPRPALQMLPLETQWRCVQDQNRHIETVIA 274
                |.|:.:.|.   .:||..|.|                                    ||:.
 Frog   290 ----SNVSHNYARWVLSQPCTVLHL------------------------------------TVLR 314

  Fly   275 DSKRKLLANEDGGSASASGSGSPDSYMDSPETETYVVELHKNVYG--LGITVAGYVCEEEDLSGI 337
            :.:       .|..|...|.|.      |...|::.:.|:|....  |||.:.    ...|.||:
 Frog   315 ERR-------FGSRAHGHGDGG------SQRDESFHITLNKRGSNEQLGIKLV----RRTDESGV 362

  Fly   338 FVKSIIEGSAAETSGQIQINDRIVAVDGRSLSGVTNHQAVELLRNTDIVVHLTLERFLRGRKYEH 402
            |:..::||..|...|::..|||::|::|..|...|...|.::::.:...|:||:.|
 Frog   363 FILDLLEGGLAAQDGRLHSNDRVLAINGLDLKHGTPELAAQIIQGSGERVNLTVSR--------- 418

  Fly   403 LQVALTEIKGTSAPSGLDR----SQDKDQDQESQLSMPGS-PSIATLSWLPPKSLDADSIATEGD 462
                    .|...|..:.|    :|.....|:.....|.: ..:|.......|.:   ::..|..
 Frog   419 --------PGKHQPGNITRDLGMNQPHHHTQQVYHHRPSAHKDLAQCVKCQEKHI---TVKKEPQ 472

  Fly   463 EAVDAEYVGISGAEDEFIELPSRDTVESNMSHVLDRSDHSGGLTKDQVPRISPIVPLTNGRSLIL 527
            |::.....|..|::..  |||.  .|.|...|        |.|.:|...:...::...||  :.|
 Frog   473 ESLGMTVAGGRGSKSG--ELPI--FVTSVQPH--------GCLARDSRIKRGDVLLSING--IDL 523

  Fly   528 ADDSGNDTDEQCAEPETETAQARKGSKPETERVKDLGDTKTDTDPDPDLDPGQMPTPTNEAPVKA 592
            .:.|.::.........|.:..:.|..:.|....:..|..:..|..:.:.|....|:
 Frog   524 TNLSHSEAVAMLKASATSSVVSLKAIEVEVIEEQTPGKEEMSTVSENEYDASWSPS--------- 579

  Fly   593 ASPTAASLRVAWKSLGISLEGTVDVEC--------------GIEKRPHH-----YIRSILADGPV 638
                    .|.|..|...|....||..              |.|:  :|     :|::|:...|.
 Frog   580 --------WVMWLGLPSCLHSCHDVVLRRSSLGSWGFSIVGGYEE--NHTNQPFFIKTIVLGTPA 634

  Fly   639 GRQGILRPGDELLQVNEHKLQGLRHIEVVKILKELPARVKL 679
            ...|.|:.||.::.||.....|:.|..:|.:|||...:|.|
 Frog   635 YYDGRLKCGDMIIAVNGLSTVGMSHSALVPMLKEQRNKVTL 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15803	NP_001287388.1	PDZ4_MUPP1-like	592..683	CDD:467156	26/107 (24%)
		PDZ5_MUPP1-like	763..859	CDD:467157
		PDZ2_MUPP1-like	11..90	CDD:467155	9/53 (17%)
		PDZ3_MUPP1-like	307..393	CDD:467253	25/87 (29%)
lnx2	NP_001072606.1	mRING-HC-C3HC3D_LNX2	43..87	CDD:319694
		PDZ1_LNX1_2-like	227..315	CDD:467165	20/144 (14%)
		PDZ2_LNX1_2-like	336..418	CDD:467166	24/85 (28%)
		PDZ3_LNX1_2-like	463..550	CDD:467167	20/103 (19%)
		PDZ4_LNX1_2-like	594..682	CDD:467168	22/84 (26%)