Protein Alignment CG15803 and stxbp4

DIOPT Version :10

• Sequence 1: NP_001287388.1
• Gene: CG15803 / 42206
• FlyBaseID: FBgn0038606
• Length: 880
• Species: Drosophila melanogaster
• Sequence 2: NP_001037969.1
• Gene: stxbp4 / 733742
• XenbaseID: XB-GENE-973737
• Length: 516
• Species: Xenopus tropicalis
• Alignment Length: 660
• Identity: 121/660 - (18%)
• Similarity: 218/660 - (33%)
• Gaps: 228/660 - (34%)

  Fly    10 VEVIDLINDGNGLGFILVGGRSTG----VVIKALTPGGVAERDGRLQLGDHLLQIGEVNLRGFSS 70
            |::|.:..: ..||..||||.|..    :.||.:.|||...:||||:.||.|:.:.:..|.|.|.
 Frog    12 VQIITVTKE-TSLGLSLVGGISRAEEPLIYIKDIIPGGDCHKDGRLKSGDQLVSVNKELLVGVSC 75

  Fly    71 EQVATVLRQTGAQVRLIVARPVEPTAIDYQTLACQAPIIPTKLLSDPEELSRHLFQNPSFATAAV 135
            ||...:|.:  |::|                   :.|:.....:...|||..|:.
 Frog    76 EQAKCILNR--AKLR-------------------KGPVWEIAYIRPVEELQNHIL---------- 109

  Fly   136 AAAAAAAAAAGSGSDGDVGGGGVLDVASLVGLVRGGPAEGTELSAVE------PQPSAAVLQLQQ 194
                                                ||:|....|::      ..||||...|..
 Frog   110 ------------------------------------PADGCVKGAMDFMPNRISSPSAAKANLSS 138

  Fly   195 LSELAGDLADFPLPPIPGGGGHSMVTDSNAGQRPCPRLDLDIVPFSILSPPPRPALQMLPLETQW 259
            .|..:...|:.||              |.|.|.......|.      |:|..|..::.|.:...:
 Frog   139 ESIKSQHAAESPL--------------SAASQTYGEEEQLS------LNPSIRIKVEKLEMALNY 183

  Fly   260 RCVQDQNRHIETVIADSKRKLLANEDGGSASASGSGSPDSYMDSPETETY--VVELHKNVYGLGI 322
            ..:...         :.:::|:              ..|..:|:..|..|  .|::.:.::.|.|
 Frog   184 LGIHPN---------EEQKRLM--------------KQDLKIDANGTVEYGDFVQVARKLFTLQI 225

  Fly   323 TVAGY-----VCEEEDLSGIFVKSIIEGSAAETSGQIQINDRIVAVDGRSLSGVTNHQAVELLRN 382
            ....:     :.|:.|::     |:|:.:|.:.|....::|     |...|....|....||.:
 Frog   226 KEGDFKQEMTLSEDRDIT-----SLIDSNANKDSLHPSVSD-----DPEQLRRERNEAYAELKK- 279

  Fly   383 TDIVVHLTLERFLRGRK-----YEHLQVALTEIKGTSAPSGLDRSQDKDQDQESQLSMPGSPSIA 442
                   ..||..:..|     .|.|:....|.||....:...|::
 Frog   280 -------LKERLQKSEKNRSQLSEELENVKQEAKGAIEEARALRNR------------------- 318

  Fly   443 TLSWLPPKSLDADSIATEGDEAVDAEYVGISGAEDEFIELPSRDTVESNMSHVLDRSDHSGGLTK 507
                     :....:|......::.:|       :|.|.|     :|:.::.:..:.....|.||
 Frog   319 ---------IHLAEVAQSQASGMETDY-------EEVIRL-----LEAEVAELKAQLLKCSGQTK 362

  Fly   508 DQVPRISPIVPLTNGRSLILADDSGNDTDEQCAEPETETAQARKGSKPETERVKDLGDTKTDTDP 572
            |.|..:       ..|:.:|.          |...::|  .|||..:..||:::...:...|...
 Frog   363 DNVQDL-------KRRASVLC----------CQLRKSE--MARKAFEVTTEKLQQFAENVCDIIS 408

  Fly   573 DPD---LDPGQMPTP-TNEAPVKAASPT----AASLRVAWKSLGISLEGTVDVEC---GIEKRPH 626
            |..   |:|.:..:| :::..:....|:    .|::....:.|..|:...||.:|   |:|:
 Frog   409 DDSANMLNPSEKGSPFSSKTLMTRLKPSRHDIIAAMAAEARDLARSVRSMVDTQCLPYGLEE--- 470

  Fly   627 HYIRSILADG 636
                :..|||
 Frog   471 ----AYTADG 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15803	NP_001287388.1	PDZ4_MUPP1-like	592..683	CDD:467156	12/52 (23%)
		PDZ5_MUPP1-like	763..859	CDD:467157
		PDZ2_MUPP1-like	11..90	CDD:467155	28/82 (34%)
		PDZ3_MUPP1-like	307..393	CDD:467253	16/92 (17%)
stxbp4	NP_001037969.1	PDZ1_hSTXBP4-PDZ2_GgSTXBP4-like	12..99	CDD:467184	30/108 (28%)
		Smc	<215..>401	CDD:440809	43/262 (16%)
		WW	464..493	CDD:459800	5/20 (25%)