DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15803 and CG10939

DIOPT Version :9

Sequence 1:	NP_001287388.1	Gene:	CG15803 / 42206	FlyBaseID:	FBgn0038606	Length:	880	Species:	Drosophila melanogaster
Sequence 2:	NP_524712.1	Gene:	CG10939 / 44155	FlyBaseID:	FBgn0010620	Length:	296	Species:	Drosophila melanogaster

Alignment Length:	317	Identity:	59/317 - (18%)
Similarity:	104/317 - (32%)	Gaps:	97/317 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   581 MPTPTNEAPVKAASPTAASLRVAWKSLGISLEGTVDVECGIEKRPH----------------HYI 629
            |.|||  :|.....||              |...|...|.|.|||.                .:|
  Fly     1 MSTPT--SPKTPTPPT--------------LPPGVTKTCHIVKRPDFDGYGFNLHSEKVKPGQFI 49

  Fly   630 RSILADGPVGRQGILRPGDELLQVNEHKLQGLRHIEVVKILKELPARVKLVCARGTHVPSVINTS 694
            ..:.||.|....| |:.||.:|:||...:....|.:||..:|.:...|:|:         :|:.
  Fly    50 GKVDADSPAEAAG-LKEGDRILEVNGVSIGSETHKQVVARIKAIANEVRLL---------LIDV- 103

  Fly   695 QNPEAFETRSLLPGGHQSLQNLLSKAQSESSLYTSSTATLTDAGAAAGGSGGTAGGGARSKSLEN 759
             :.:|.|.:...|                             ..||..|:|..:..|......|.
  Fly   104 -DGKALEVKPASP-----------------------------PAAACNGNGSASQNGYEGTKQEM 138

  Fly   760 VSGLALWSCEVTAVDIEKTEQGFGFSILDYQDPLDSEGSVIVIRGL--IRGGAAEATNEIYPGDR 822
            ...    |..::::.:..|::....|.:.....:::....:|.||:  :....|.....:..|.:
  Fly   139 PGA----SANISSISMVSTKRSSNASSIQSGSTMNASDLDVVDRGIPAVAAPVAITPPPVQNGSK 199

  Fly   823 LMSVGDRLLQGLELDEAVSILKAMPPGLTRLGICRPLSASDSNSNSNIASPLGDSTS 879
            ..|         .::....:....||..|:.||         |:|.::.:..|:.|:
  Fly   200 PSS---------PINNNTLMSTPPPPSATKAGI---------NNNGSVYNTNGNGTN 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15803	NP_001287388.1	PDZ_signaling	17..89	CDD:238492
		PDZ	307..393	CDD:214570
		PDZ_signaling	605..680	CDD:238492	23/90 (26%)
		PDZ	773..858	CDD:214570	13/86 (15%)
CG10939	NP_524712.1	PDZ_signaling	20..101	CDD:238492	22/90 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900