DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15803 and C50F7.3

DIOPT Version :9

Sequence 1:	NP_001287388.1	Gene:	CG15803 / 42206	FlyBaseID:	FBgn0038606	Length:	880	Species:	Drosophila melanogaster
Sequence 2:	NP_501268.1	Gene:	C50F7.3 / 183682	WormBaseID:	WBGene00016843	Length:	313	Species:	Caenorhabditis elegans

Alignment Length:	346	Identity:	70/346 - (20%)
Similarity:	112/346 - (32%)	Gaps:	131/346 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 HLFQNPSFATAAVAAAAAAAAAAGSGSDGDVGGGGVLDVASLVGLVRGGPAEGTELSAVEPQPSA 187
            |||:...|:|...|             :.::|    :::.|.|  |...|.|......::.....
Worm    22 HLFETLEFSTVVKA-------------EDNIG----IELKSSV--VVSIPFESPWTGLIKVGDIL 67

  Fly   188 AVLQLQQLSELAGDLADFPLPPIPGGGGHSMVTDSNAGQRPCPRLDLDIVPFSILSPPPR--PAL 250
            ..|...|:.. .|.||.|....|.|              :||.::...::.|....|.|.  |.|
Worm    68 VYLNGYQIGG-QGVLARFIQTIING--------------QPCAKMTYKVIRFKRHIPRPSGFPPL 117

  Fly   251 QMLPLETQWRCVQDQNRHIETVIADSKRKLLANEDGGSASASGSGSPDSYMDSPETETYVVELHK 315
            |               :|                             :||    .|:|.|:...|
Worm   118 Q---------------KH-----------------------------ESY----STDTLVLYNLK 134

  Fly   316 NVYGLGITVAGYVCEEEDLSG-IFVKSIIEGSAAETSGQIQINDRIVAVDG-RSLSGVTNHQAVE 378
            .|:.||:.:       :::.| |.|..::|.|..:.:  ..:.:.|:.||| :.||....::.|.
Worm   135 KVFHLGLDI-------KEIEGKIVVCDLVENSLGDMT--FSVGETILDVDGEKPLSCTGFNERVR 190

  Fly   379 ---LLRNTDIVVHLTLERFLRGRKYEHLQVALTEIKGTSAPSGLDRSQDKDQDQESQLSMPGSPS 440
               |:||..:|.                    .||..|.....|.|:|.....:|       :|.
Worm   191 KSLLIRNYCLVT--------------------VEIPSTDPLKNLLRNQITKTVKE-------APR 228

  Fly   441 IATLSWLPPKSLDADSIATEG 461
            |..   |||   ||.:...||
Worm   229 IHK---LPP---DAAAYGAEG 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15803	NP_001287388.1	PDZ_signaling	17..89	CDD:238492
		PDZ	307..393	CDD:214570	22/90 (24%)
		PDZ_signaling	605..680	CDD:238492
		PDZ	773..858	CDD:214570
C50F7.3	NP_501268.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900