DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15803 and C46H11.6

DIOPT Version :9

Sequence 1:	NP_001287388.1	Gene:	CG15803 / 42206	FlyBaseID:	FBgn0038606	Length:	880	Species:	Drosophila melanogaster
Sequence 2:	NP_491502.1	Gene:	C46H11.6 / 183523	WormBaseID:	WBGene00016730	Length:	342	Species:	Caenorhabditis elegans

Alignment Length:	310	Identity:	67/310 - (21%)
Similarity:	108/310 - (34%)	Gaps:	88/310 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   446 WLPPKSLDADSIATEGDEAVDAEYVGISGAEDEFIELPSRDTVESN----MSHVLDRSDHSGGLT 506
            ||.|...:.:::.......:|.:.||          .|:.:.:..|    :|.:...|.::|.:.
Worm    17 WLTPIPQNVETVNMTVSFKIDEKDVG----------KPANEVIRINENSMVSFLSTNSFYNGLIL 71

  Fly   507 KDQVPRISPIVPLTNGRSLILADDSGNDTDEQCAEPETETAQA----RKGSKPET-ERVKDLGDT 566
            .|::.::       ||.       |||.:..|....:.||...    ||...|.| ||:|..|..
Worm    72 SDKIVKV-------NGA-------SGNISKYQTELMKGETCSVEVTRRKNIIPATRERLKKSGCV 122

  Fly   567 -KTDTDPDPDLDPGQMPTPTNEAPVKAASPTAASLRVAWKSLGISLEGTVDVECGIEKR--PHHY 628
             :.|                |...|.....|:     |.||..:.:..|...:.||..|  |
Worm   123 LRRD----------------NTCFVIEVEKTS-----AMKSATVGVTVTYIQKRGIVTRIEP--- 163

  Fly   629 IRSILADGPVGRQGILRPGDELLQVNE--------------HKLQGLRHIEVVKILKELPARVKL 679
              |.||....||      ||.::.:||              .||.|:...|.|..|.|.|..|:
Worm   164 --SSLASIFFGR------GDLIMDINEESILNAEKNDDFIREKLSGILKGEKVTFLVERPVSVE- 219

  Fly   680 VCARGTHVPSVINTSQNPEAFETRSLLPGGHQSLQ---NLLSKAQSESSL 726
              :..|....:.:.:.:|:.......:..|..:..   |:|.|.|.:|.|
Worm   220 --SANTLRHLIESVAPDPDVKMANDAICIGRNASNMHYNVLKKLQPKSIL 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15803	NP_001287388.1	PDZ_signaling	17..89	CDD:238492
		PDZ	307..393	CDD:214570
		PDZ_signaling	605..680	CDD:238492	25/90 (28%)
		PDZ	773..858	CDD:214570
C46H11.6	NP_491502.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900