DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15803 and mics-1

DIOPT Version :9

Sequence 1:	NP_001287388.1	Gene:	CG15803 / 42206	FlyBaseID:	FBgn0038606	Length:	880	Species:	Drosophila melanogaster
Sequence 2:	NP_001343863.1	Gene:	mics-1 / 179475	WormBaseID:	WBGene00011890	Length:	293	Species:	Caenorhabditis elegans

Alignment Length:	215	Identity:	52/215 - (24%)
Similarity:	84/215 - (39%)	Gaps:	66/215 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   310 VVELHKNVYGLGITVAGYVCEEEDLS--GIFVKSIIEGSAAETSGQIQINDRIVAVDGRSLSGVT 372
            |||:.|...|.|..:.|.......:.  ||:|.|:  .|.:::.|.::..|:|::.||..::..|
Worm    73 VVEIEKTSKGFGFNIVGGTDNPHFVGDIGIYVSSV--NSESKSYGVVRTGDKILSFDGIDMTYKT 135

  Fly   373 NHQAVELLRNTDIVVHLTLERFLRGRKYEHLQVALTEI-------------------KGTSAPSG 418
            :.:|||:.|:..| .|:.  :.|..|:|.|||...|:.                   ..|..|..
Worm   136 HDEAVEVFRSVKI-GHVA--KMLIDREYLHLQEDRTQTPTASVSITPQVTPQTRSTQNNTDTPKS 197

  Fly   419 LDRSQDK---------------------DQDQESQLS-MPGSPSI---------ATLSWLPPKSL 452
            :..|:.|                     ::|.:|..| .|.:.||         ..||.|.|::
Worm   198 MSHSESKSRLTSHGLSAVIERIRGKVYEEEDAQSVTSYAPSTHSIIDDVPRTPRKPLSLLDPRN- 261

  Fly   453 DADSIATEGDEAVDAEYVGI 472
              :|..||      |.||.|
Worm   262 --NSWLTE------ALYVSI 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15803	NP_001287388.1	PDZ_signaling	17..89	CDD:238492
		PDZ	307..393	CDD:214570	24/84 (29%)
		PDZ_signaling	605..680	CDD:238492
		PDZ	773..858	CDD:214570
mics-1	NP_001343863.1	PDZ_signaling	71..145	CDD:238492	21/73 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810