DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15803 and smz-2

DIOPT Version :9

Sequence 1:	NP_001287388.1	Gene:	CG15803 / 42206	FlyBaseID:	FBgn0038606	Length:	880	Species:	Drosophila melanogaster
Sequence 2:	NP_491965.1	Gene:	smz-2 / 172415	WormBaseID:	WBGene00020661	Length:	274	Species:	Caenorhabditis elegans

Alignment Length:	193	Identity:	51/193 - (26%)
Similarity:	76/193 - (39%)	Gaps:	64/193 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 GLGFILVGGRSTGVVIKALTPGGVAERDGRLQLGDHLLQIGEVNLRGFSSEQVATVLR----QTG 81
            |||......|   |::..:.||.:||:  .|.|||||..:..:.:   |.:.||..|.    |..
Worm   124 GLGIKHFQNR---VLVSRVDPGSLAEK--CLVLGDHLCDVDGIPV---SDKDVARDLLVKNIQEK 180

  Fly    82 AQVRLIVARPVEPTAIDYQTLACQAPIIPTKLLSDPEELSRHLFQNPSFATAAVAAAAAAAAAAG 146
            .:|..:|.|   |.:||.:..|.||             |:.:|.|.||..
Worm   181 GKVTFVVER---PDSIDAKQWAKQA-------------LATNLMQPPSVQ--------------- 214

  Fly   147 SGSDGDVGGGGVLDVAS-----LVGLVRGGPAEGTELSAVEPQPSA---AVLQLQQLSELAGD 201
              .:.||.|     :||     |.||  ..||:    ||:...|:|   ::::..|..|:..|
Worm   215 --MNEDVKG-----IASQYRQALPGL--KPPAK----SAMSTGPNARRVSIIEQTQTHEIGHD 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15803	NP_001287388.1	PDZ_signaling	17..89	CDD:238492	21/71 (30%)
		PDZ	307..393	CDD:214570
		PDZ_signaling	605..680	CDD:238492
		PDZ	773..858	CDD:214570
smz-2	NP_491965.1	PDZ_signaling	7..77	CDD:238492
smz-2	NP_491965.1	PDZ_signaling	114..188	CDD:238492	21/71 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900