DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15803 and Pdzd3

DIOPT Version :9

Sequence 1:	NP_001287388.1	Gene:	CG15803 / 42206	FlyBaseID:	FBgn0038606	Length:	880	Species:	Drosophila melanogaster
Sequence 2:	NP_573489.2	Gene:	Pdzd3 / 170761	MGIID:	2429554	Length:	498	Species:	Mus musculus

Alignment Length:	341	Identity:	81/341 - (23%)
Similarity:	118/341 - (34%)	Gaps:	100/341 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   605 KSLGISLE---GTVDVECGIEKRPHHYIRSILADGPVGRQGILRPGDELLQVNEHKLQGLRHIEV 666
            |:.|..|:   |..|          |.:..:.......||| ||.||.:|.||.:.:....|..|
Mouse    58 KTFGFHLQQHLGKAD----------HVVCRVDPGTSAQRQG-LREGDRILAVNNNIVAHEDHAVV 111

  Fly   667 VKILKELPARVKLVCARGTHVPSVINTSQNPEAFETRSLLPGGHQSLQNLLSKAQSESSLYTSST 731
            |:.::....|| |:.....||..|....|..:||...:|..|....|.:::   :.|.....|.|
Mouse   112 VRYIRASGPRV-LLTVLAQHVHDVARVLQGSDAFLCPTLPSGVRPRLCHVV---KDEGGFGFSVT 172

  Fly   732 A-------TLTDAGAAAGGSGGTAG-------GGARSKSLENVSGLALWSC--EVT--------- 771
            .       .:..||.||..:|...|       |.:..|...|.....||..  :||
Mouse   173 HGSRGPFWLVLSAGGAAERAGVPPGARLLEVNGASVEKLTYNQLNRKLWQSGDQVTLLVAGLEVE 237

  Fly   772 -------------------------AVDIEKTEQGFGFSILDYQDPLDSE-GSVI--VIRGLIRG 808
                                     .::|||..:|||| :|..:..||.. |..:  |..||...
Mouse   238 EQCHQLGMPLAAPLAEGWALPAKPRCLNIEKGPEGFGF-LLREEKGLDGRLGQFLWDVDPGLPAD 301

  Fly   809 GAAEATNEIYPGDRLMSVGDRLLQGLELDEAVSILKAMPPGLTRLGICRPLSASDSNS------- 866
            .|.     :..||||::|....:.||..:|.||.::|.       |.|..|...|..:
Mouse   302 KAG-----MKAGDRLVAVAGESVDGLGHEETVSRIRAQ-------GSCVSLIVVDPEADRFFSMV 354

  Fly   867 ---------NSNIASP 873
                     |:.||:|
Mouse   355 RLSPLLFLENTEIAAP 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15803	NP_001287388.1	PDZ_signaling	17..89	CDD:238492
		PDZ	307..393	CDD:214570
		PDZ_signaling	605..680	CDD:238492	21/77 (27%)
		PDZ	773..858	CDD:214570	28/87 (32%)
Pdzd3	NP_573489.2	PDZ_signaling	47..127	CDD:238492	22/80 (28%)
		PDZ_signaling	155..232	CDD:238492	17/79 (22%)
		PDZ	260..345	CDD:214570	29/97 (30%)
		PDZ_signaling	407..471	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900