Protein Alignment CG15803 and Il16

DIOPT Version :9

• Sequence 1: NP_001287388.1
• Gene: CG15803 / 42206
• FlyBaseID: FBgn0038606
• Length: 880
• Species: Drosophila melanogaster
• Sequence 2: NP_001347016.1
• Gene: Il16 / 16170
• MGIID: 1270855
• Length: 1424
• Species: Mus musculus
• Alignment Length: 1105
• Identity: 214/1105 - (19%)
• Similarity: 343/1105 - (31%)
• Gaps: 406/1105 - (36%)

  Fly    19 GNGLGFILVGGRS-------TGVVIKALTPGGVAERDGRLQLGDHLLQIGEVNLRGFSSEQVATV 76
            |.|||   :|..|       :|:.:..|:||.||..||||:.||.:::|.:..:...:..:|.|:
Mouse   462 GVGLG---IGLCSIPYFQCISGIFVHTLSPGSVAHLDGRLRCGDEIVEINDSPVHCLTLNEVYTI 523

  Fly    77 LRQTG-AQVRLIVARPVEPTAIDYQTLACQAPIIP-TKLLSDPEELS-------------RHLFQ 126
            |.... ..|.:||:|..:|...:.|.....|..:. .|...|..:.|             |...:
Mouse   524 LSHCDPGPVPIIVSRHPDPQVSEQQLKEAVAQAVEGVKFGKDRHQWSLEGVKRLESSWHGRPTLE 588

  Fly   127 NPSFATAAVAAAAAAAAAAGSGSD-----GDVGGGGVLDVASLVGLVRGGPAEGTELSAVEPQ-P 185
            ......:|.....|......|.||     |..||......|......|.|......||..|.| |
Mouse   589 KEREKHSAPPHRRAQKIMVRSSSDSSYMSGSPGGSPCSAGAEPQPSEREGSTHSPSLSPGEEQEP 653

  Fly   186 SAAV----------------------LQLQQLSEL--AGDLADFPLPP----------------- 209
            ...|                      |:|::..|:  ....:..|.||
Mouse   654 CPGVPSRPQQESPPLPESLERESHPPLRLKKSFEILVRKPTSSKPKPPPRKYFKNDSEPQKKLEE 718

  Fly   210 ---IPGGGGHSMVT--------------DSNAGQRPC-------PRLDL------------DIVP 238
               :....||::.|              :..||:.||       |....            ...|
Mouse   719 KEKVTDPSGHTLPTCSQETRELLPLLLQEDTAGRAPCTAACCPGPAASTQTSSSTEGESRRSASP 783

  Fly   239 FSILSPPPRPALQM---------LPLETQWRCVQD----------QNRHIETVIADSKRKLLANE 284
            .:..||...|.|:.         :..|..|..:.|          ...|..|.:..:..  |..|
Mouse   784 ETPASPGKHPLLKRQARMDYSFDITAEDPWVRISDCIKNLFSPIMSENHSHTPLQPNTS--LGEE 846

  Fly   285 DGGSASASGSGSPDSYMDSPETETYVVELHKNVYGLGITVAGYVCEE-----EDLSGI------- 337
            ||      ..|.|:..:...:.......::|:..|..:.....|..:     :.|.|:
Mouse   847 DG------TQGCPEGGLSKMDAANGAPRVYKSADGSTVKKGPPVAPKPAWFRQSLKGLRNRAPDP 905

  Fly   338 ----FVKSIIEG----------------------SAAETSGQIQINDRIV--------------- 361
                .|.|.|:.                      |:.|..|..|:.||.|
Mouse   906 RRPPEVASAIQPTPVSRDPPGPQPQASSSIRQRISSFENFGSSQLPDRGVQRLSLQPSSGETTKF 970

  Fly   362 --AVDGRSLSGVTNHQAVELLRNTDIVVHLTLERFLRGRKYEHLQVALTEIK--GTSAPSGLDRS 422
              ..||...||:....|....:                    |.|   ||::  .|:.|:.   |
Mouse   971 PGKQDGGRFSGLLGQGATVTAK--------------------HRQ---TEVESMSTTFPNS---S 1009

  Fly   423 QDKDQDQESQLSMPGSPSIATLSWLPP------KSLDADS----IATEGDEAVDAEYVGISGAED 477
            :.:|.      .:|.||        ||      |:|..|.    :.|:.:   |.:..|:.....
Mouse  1010 EVRDP------GLPESP--------PPGQRPSTKALSPDPLLRLLTTQSE---DTQGPGLKMPSQ 1057

  Fly   478 EFIELPSRDT-----------------VESNMSHV-------LDRSDHSGGLTKDQVPRISPIVP 518
            .....|...|                 :.|.:|..       |..|...|.:|.....|:||..|
Mouse  1058 RARSFPLTRTQSCETKLLDEKASKLYSISSQLSSAVMKSLLCLPSSVSCGQITCIPKERVSPKSP 1122

  Fly   519 LTN-----GRSLILADDSG--------NDTDEQCAEP-ETE-----TAQARKG-----SKPETER 559
            ..|     |....:|.|:|        .:..|...|| |||     ::||.:.     |..|.|:
Mouse  1123 CNNSSAAEGFGEAMASDTGFSLNLSELREYSEGLTEPGETEDRNHCSSQAGQSVISLLSAEELEK 1187

  Fly   560 VKDLGDTKTDTDPDPDLDPGQMPTPTNEAPVKAASPTAASL--RVAWKSLGISLEGTVDVECGIE 622
            :  :.:.:.       ||         ||.:|.......::  :.....||.||.|..|:|..:.
Mouse  1188 L--IEEVRV-------LD---------EATLKQLDSIHVTILHKEEGAGLGFSLAGGADLENKVI 1234

  Fly   623 KRPHHYIRSILADGPVGRQGILRPGDELLQVNEHKLQGLRHIEVVKILKEL--PARVKLVCARGT 685
            .     :..:..:|...::|.::.|:|:|.:|...|:|..|.:.:.||::.  |.:..:|..|.|
Mouse  1235 T-----VHRVFPNGLASQEGTIQKGNEVLSINGKSLKGATHNDALAILRQARDPRQAVIVTRRTT 1294

  Fly   686 HVPSVINTSQNPEAFETRSLLPGGHQSLQNLLSKAQSESSLYTSSTATLTDAGAAAGGSGGTAGG 750
                                              .::...|.:|     ||:.|:|..:
Mouse  1295 ----------------------------------VEATHDLNSS-----TDSAASASAA------ 1314

  Fly   751 GARSKSLENVSGLALWSCEVT--AVDIEKTEQGFGFSILDYQDPLDSEGSVIVIRGLIRGGAAEA 813
                      |.:::.|.|.|  .|.:|||..|.|||:         ||.    :|.:.|.....
Mouse  1315 ----------SDISVESKEATVCTVTLEKTSAGLGFSL---------EGG----KGSLHGDKPLT 1356

  Fly   814 TNEIY----------PGDRLMSVGDRLLQGLELDEAVSILKAMPPGLTRLGI------CRPLSAS 862
            .|.|:          |||.::.:....:|||...||.:::||:|.|...:.|      |:..:||
Mouse  1357 INRIFKGTEQGEMVQPGDEILQLAGTAVQGLTRFEAWNVIKALPDGPVTIVIRRTSLQCKQTTAS 1421

  Fly   863  862
            Mouse  1422  1421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15803	NP_001287388.1	PDZ_signaling	17..89	CDD:238492	24/77 (31%)
		PDZ	307..393	CDD:214570	20/140 (14%)
		PDZ_signaling	605..680	CDD:238492	19/76 (25%)
		PDZ	773..858	CDD:214570	28/100 (28%)
Il16	NP_001347016.1	PDZ_signaling	316..391	CDD:238492
		PDZ_signaling	454..536	CDD:238492	23/76 (30%)
		Atrophin-1	<620..931	CDD:331285	49/318 (15%)
		PDZ_signaling	1206..1283	CDD:238492	18/81 (22%)
		PDZ_signaling	1328..1409	CDD:238492	26/93 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900