back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment naz and CBR1

DIOPT Version :9

Sequence 1:	NP_001287387.1	Gene:	naz / 42204	FlyBaseID:	FBgn0286852	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_001748.1	Gene:	CBR1 / 873	HGNCID:	1548	Length:	277	Species:	Homo sapiens

Alignment Length:	295	Identity:	80/295 - (27%)
Similarity:	121/295 - (41%)	Gaps:	78/295 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 IVVVTGGNSGIGFEIAQALAGR-GGRIILACRNLEAGKRAAAIIKRELGCRTPLNSLDEDDNPED 114
            :.:|||||.|||..|.:.|... .|.::|..|::..|:.|...::.| |.....:.||.|
Human     7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-GLSPRFHQLDID----- 65

  Fly   115 RYFVEARYLDLCSLRSVHHFAGQLMAEFERIDVLVNNAGVVFANTQMPTEDGFERHSQVNYLAPF 179
                     ||.|:|::..|   |..|:..:||||||||:.| ....||.  |...::|.....|
Human    66 ---------DLQSIRALRDF---LRKEYGGLDVLVNNAGIAF-KVADPTP--FHIQAEVTMKTNF 115

  Fly   180 LLTH----LLLPHLQRSEQGRILFVSA----HAHQGAKIDFDDPLN---------VGTWSVKF-- 225
            ..|.    .|||.::  .|||::.||:    .|.:....:......         ||..: ||
Human   116 FGTRDVCTELLPLIK--PQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMN-KFVE 177

  Fly   226 ------HARE-----AFAHSKLCVLLATRWMAREL----KGTSVTVNCCTPGLVRGTRHFRNSPL 275
                  |.:|     |:..:|:.|.:.:|..||:|    ||..:.:|.|.||.||
Human   178 DTKKGVHQKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVR---------- 232

  Fly   276 MSSLCVKAVTYPWMWLFMKNAYEGAQCAIRLATDP 310
             :.:.....|        |:..|||:..:.||..|
Human   233 -TDMAGPKAT--------KSPEEGAETPVYLALLP 258

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.