Protein Alignment naz and DHRS12

DIOPT Version :9

• Sequence 1: NP_001287387.1
• Gene: naz / 42204
• FlyBaseID: FBgn0286852
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_001364858.1
• Gene: DHRS12 / 79758
• HGNCID: 25832
• Length: 320
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 84/312 - (26%)
• Similarity: 129/312 - (41%)
• Gaps: 66/312 - (21%)

  Fly    42 PND--NQIKEQIVVVTGGNSGIGFEIAQALAGRGGRIILACRNLEAGKRAAAIIKRELGCRTP-L 103
            |:|  .||..::.:|||||||||...|..:|.|||.:.|.||:....:.|...|.||.|.:.. |
Human    31 PHDLEVQIPGRVFLVTGGNSGIGKATALEIAKRGGTVHLVCRDQAPAEDARGEIIRESGNQNIFL 95

  Fly   104 NSLDEDDNPEDRYFVEARYLDLCSLRSVHHFAGQLMAEFERIDVLVNNAGVVFANTQMPTEDGFE 168
            :.:|..|..:...|||       :.:..|           ::.||:||||.: .|.:..||||.|
Human    96 HIVDLSDPKQIWKFVE-------NFKQEH-----------KLHVLINNAGCM-VNKRELTEDGLE 141

  Fly   169 RHSQVNYLAPFLLTHLLLPHLQRSEQGRILFVSAHAHQGAKIDFDDPLNVGTWSVKFHAREAFAH 233
            ::...|.|..::||..|:|.|::....|::.||:......|::.:|..:..|   .|.....:|.
Human   142 KNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSERT---PFDGTMVYAQ 203

  Fly   234 SK-LCVLLATRWMARELKGTSVTVNCCTPGLVRGTRHF------------RNSPLMSSLCVKAVT 285
            :| ..|:|..||....            |.:     ||            ||...:..:..:|.|
Human   204 NKRQQVVLTERWAQGH------------PAI-----HFSSMHPGWADTPDRNEQELRKVVGEAQT 251

  Fly   286 YPWMWLFMKNAYEGAQCAIRLATDPQLKEVTGEYFNDCEIAASSVTGQDKEL 337
            ...:..|::......:|      .||     |...||.|...||..|:...|
Human   252 ASPLPRFLEIMMHEGKC------QPQ-----GHSSNDLEACWSSGGGEQNSL 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
naz	NP_001287387.1	FabG	47..318	CDD:223959	73/284 (26%)
		retinol-DH_like_SDR_c_like	50..342	CDD:212492	80/302 (26%)
DHRS12	NP_001364858.1	NADB_Rossmann	40..>235	CDD:419666	64/233 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810