Protein Alignment naz and dhrs12

DIOPT Version :10

• Sequence 1: NP_732328.1
• Gene: naz / 42204
• FlyBaseID: FBgn0286852
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_001070025.1
• Gene: dhrs12 / 556393
• ZFINID: ZDB-GENE-060929-1134
• Length: 318
• Species: Danio rerio
• Alignment Length: 312
• Identity: 81/312 - (25%)
• Similarity: 140/312 - (44%)
• Gaps: 51/312 - (16%)

  Fly    44 DNQIKEQIVVVTGGNSGIGFEIAQALAGRGGRIILACRNLEAGKRAAAIIKRELGCRTPLNSLDE 108
            |..:..:..::||.|||||...|..:|.|||.:.|.|||.:..:.|          |..:....:
Zfish    35 DVSVNGRSFIITGANSGIGKAAAYEIAKRGGTVHLVCRNKDRAEEA----------RKDIVEQSK 89

  Fly   109 DDNPEDRYFVEARYLDLCSLRSVHHFAGQLMAEFERIDVLVNNAGVVFANTQMPTEDGFERHSQV 173
            .:|      |....:|:.|.|.|..||.. .::...:.||:||||.: .|.:..||||.|::...
Zfish    90 SEN------VHVHLVDMSSPRKVWEFASG-FSQNHNLHVLINNAGCM-VNQRELTEDGLEKNFAT 146

  Fly   174 NYLAPFLLTHLLLPHLQRSEQGRILFVSAHAHQGAKIDFDD-PLNVGTWSVKFHAREAFAHSKLC 237
            |.|..::||..|:|.|:|||..|::.||:......|::.:| ....|:    |....|:|.:|..
Zfish   147 NTLGTYILTTALIPTLKRSENPRVITVSSGGMLVQKLNVEDLQFEKGS----FDGTMAYAQNKRQ 207

  Fly   238 VLLATRWMARELKGTSVTVNCCTPGLVRGTRHFRNSPLMSSLCVKAVTYPWMWLFMKNAY----E 298
            .::.|...|.:.|  .:..:...||       :.::|.:.|      :.|..:..|||..    :
Zfish   208 QVIMTEQWATQHK--EIHFSSMHPG-------WADTPAVRS------SMPDFYEKMKNKLRTEAQ 257

  Fly   299 GAQCAIRLA-TDPQLKEVTGEYFNDCEIAASSV--------TGQDKELAKKL 341
            ||...:.|| :|...::.:|.:|.|.:..::.:        ..:|::|...|
Zfish   258 GADTVVWLAVSDAASRQPSGLFFQDRKAVSTHLPLAFSKTPPAEDQKLVNLL 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
naz	NP_732328.1	retinol-DH_like_SDR_c_like	50..342	CDD:212492	80/306 (26%)
dhrs12	NP_001070025.1	Rossmann-fold NAD(P)(+)-binding proteins	40..293	CDD:473865	77/289 (27%)