DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment naz and rdh13

DIOPT Version :9

Sequence 1:	NP_001287387.1	Gene:	naz / 42204	FlyBaseID:	FBgn0286852	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_001011000.1	Gene:	rdh13 / 496409	XenbaseID:	XB-GENE-965068	Length:	329	Species:	Xenopus tropicalis

Alignment Length:	341	Identity:	127/341 - (37%)
Similarity:	187/341 - (54%)	Gaps:	29/341 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 TIAALTVGIVITVRTLMSGQRCPNDNQIKEQIVVVTGGNSGIGFEIAQALAGRGGRIILACRNLE 84
            ::....:|..|.::....|..||:...|..|.|:|||.|:|||.|.|..||.||||||:|||::.
Frog     9 SMVGTALGGAILLKDYTGGGNCPSKASIIGQTVIVTGANTGIGKETALELAKRGGRIIMACRDMG 73

  Fly    85 AGKRAAAIIKRELGCRTPLNSLDEDDNPEDRYFVEARYLDLCSLRSVHHFAGQLMAEFERIDVLV 149
            ..:.||    |::..:| ||           :.|.||:|||.|.:|:..||..::.|.||:|||:
Frog    74 KCENAA----RDIRGKT-LN-----------HNVFARHLDLASSKSIKEFAKTIINEEERVDVLI 122

  Fly   150 NNAGVVFANTQMP---TEDGFERHSQVNYLAPFLLTHLLLPHLQRSEQGRILFVSAHAHQGAKID 211
            |||.|:    :.|   |||.||....||:|..||||:|||..::|||..||:.||:.||....||
Frog   123 NNAAVM----RCPHWKTEDNFEMQFGVNHLGHFLLTNLLLEKMKRSENSRIINVSSLAHIAGDID 183

  Fly   212 FDDPLNVGTW-SVKFHAREAFAHSKLCVLLATRWMARELKGTSVTVNCCTPGLVRGTRHFRNSPL 275
            ||| ||   | ..|::.:.|:..|||..:|.|..:|:.|:||.:|.|...|| |..|...|::.:
Frog   184 FDD-LN---WEKKKYNTKAAYCQSKLANVLFTNELAKRLQGTKLTANSLHPG-VADTELGRHTGM 243

  Fly   276 MSSLCVKAVTYPWMWLFMKNAYEGAQCAIRLATDPQLKEVTGEYFNDCEIAASSVTGQDKELAKK 340
            ..|.....:..|..|..:|:..:.||.::.||....|:.|:|:|||..:....:....|:|.|:|
Frog   244 HQSAFSSTILAPLFWFLVKSPKQAAQPSVYLAVAENLQGVSGKYFNALKEKEPAPQALDEESARK 308

  Fly   341 LYMQTIKTLESVTKLT 356
            |:.::.|.:.....||
Frog   309 LWEESAKLVHLEEALT 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
naz	NP_001287387.1	FabG	47..318	CDD:223959	110/274 (40%)
naz	NP_001287387.1	retinol-DH_like_SDR_c_like	50..342	CDD:212492	117/295 (40%)
rdh13	NP_001011000.1	retinol-DH_like_SDR_c	38..313	CDD:212495	118/299 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010