DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment naz and Wwox

DIOPT Version :9

Sequence 1:	NP_001287387.1	Gene:	naz / 42204	FlyBaseID:	FBgn0286852	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_006255728.1	Gene:	Wwox / 292041	RGDID:	1309927	Length:	414	Species:	Rattus norvegicus

Alignment Length:	322	Identity:	106/322 - (32%)
Similarity:	149/322 - (46%)	Gaps:	50/322 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 QIVVVTGGNSGIGFEIAQALAGRGGRIILACRNLEAGKRAAAIIKRELGCRTPLNSLDEDDNPED 114
            ::|:|||.|||||||.|::.|..|..:||||||:.....|.:.|..|.                .
  Rat   125 KVVLVTGANSGIGFETAKSFALHGAHVILACRNMSRASEAVSRILEEW----------------H 173

  Fly   115 RYFVEARYLDLCSLRSVHHFAGQLMAEFERIDVLVNNAGVVFANTQMPTEDGFERHSQVNYLAPF 179
            :..|||..|||..||||.|||....|:...:.:||.||| .||.....|:||.|...|||:|..|
  Rat   174 KAKVEAMTLDLAVLRSVQHFAEAFKAKNVPLHILVCNAG-TFALPWSLTKDGLETTFQVNHLGHF 237

  Fly   180 LLTHLLLPHLQRSEQGRILFVSAHAHQGAKI-DFDDPLNVGTWSVK---FHAREAFAHSKLCVLL 240
            .|..||...|.||...|::.||:.:|:...| |....|::...|:.   :.|..|:..||||.:|
  Rat   238 YLVQLLQDVLCRSAPARVIVVSSESHRFTDINDSSGKLDLSRLSLSSSDYWAMLAYNRSKLCNIL 302

  Fly   241 ATRWMARELKGTSVTVNCCTPGLVRGTRHFRNSPLMSSLCVKAVTYPWMWL--------FMKNAY 297
            .:..:.|.|....||.|...||.:..:...|||              |::.        |.|:..
  Rat   303 FSNELHRLLSPRGVTSNALHPGNMMFSAIHRNS--------------WVYKLLFTLARPFTKSMQ 353

  Fly   298 EGAQCAIRLATDPQLKEVTGEYFNDCEIAASSVTGQDKELAKKLYMQTIKTLESVTKLTVDR 359
            :||...:..|..|:|:.:.|.|||:|.....|...|::|.|:.|:       |...:|..||
  Rat   354 QGAATTVYCAVAPELEGLGGMYFNNCCRCLPSEEAQNEETARALW-------ELSERLIQDR 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
naz	NP_001287387.1	FabG	47..318	CDD:223959	92/279 (33%)
naz	NP_001287387.1	retinol-DH_like_SDR_c_like	50..342	CDD:212492	101/303 (33%)
Wwox	XP_006255728.1	WW	18..47	CDD:395320
		WW	60..90	CDD:238122
		human_WWOX_like_SDR_c-like	124..407	CDD:187669	104/319 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000