Protein Alignment naz and DHRSX

DIOPT Version :10

• Sequence 1: NP_732328.1
• Gene: naz / 42204
• FlyBaseID: FBgn0286852
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_660160.2
• Gene: DHRSX / 207063
• HGNCID: 18399
• Length: 330
• Species: Homo sapiens
• Alignment Length: 346
• Identity: 110/346 - (31%)
• Similarity: 171/346 - (49%)
• Gaps: 42/346 - (12%)

  Fly    13 PFATWWPTIAALTVGIVITVRTLMSGQRC------PNDNQIKEQIVVVTGGNSGIGFEIAQALAG 71
            |.:.....:....||..:.:..|:  :||      |......:::.:||||..|||:..|:.||.
Human     3 PLSAARAALRVYAVGAAVILAQLL--RRCRGGFLEPVFPPRPDRVAIVTGGTDGIGYSTAKHLAR 65

  Fly    72 RGGRIILACRNLEAGKRAAAIIKRELGCRTPLNSLDEDDNPEDRYFVEARYLDLCSLRSVHHFAG 136
            .|..:|:|..|....|:..:.||.|     .||         |:  ||..|.||.|:.|:..|..
Human    66 LGMHVIIAGNNDSKAKQVVSKIKEE-----TLN---------DK--VEFLYCDLASMTSIRQFVQ 114

  Fly   137 QLMAEFERIDVLVNNAGVVFANTQMPTEDGFERHSQVNYLAPFLLTHLLLPHLQRS----EQGRI 197
            :...:...:.||:|||||:.. .|..|.||||.|..:|||..||||:|||..|:.|    ...|:
Human   115 KFKMKKIPLHVLINNAGVMMV-PQRKTRDGFEEHFGLNYLGHFLLTNLLLDTLKESGSPGHSARV 178

  Fly   198 LFVSAHAHQGAKIDFDDPLNVGTWSVKFHAREAFAHSKLCVLLATRWMAREL--KGTSVTVNCCT 260
            :.||:..|..|:::.||..:...:|.  ||  |:|.|||.::|.|..:.|.|  :|:.||.|...
Human   179 VTVSSATHYVAELNMDDLQSSACYSP--HA--AYAQSKLALVLFTYHLQRLLAAEGSHVTANVVD 239

  Fly   261 PGLVRGTRHFRNSPLMSSLCVKAVTYPWMWLFMKNAYEGAQCAIRLATDPQLKEVTGEY-FNDCE 324
            ||:| .|..:::....:.|..|.:.    ||..|...|||..:|..|..|:|:.|.|.| :|:.|
Human   240 PGVV-NTDVYKHVFWATRLAKKLLG----WLLFKTPDEGAWTSIYAAVTPELEGVGGHYLYNEKE 299

  Fly   325 IAASSVTGQDKELAKKLYMQT 345
            ..:..|| .:::|.::|:.::
Human   300 TKSLHVT-YNQKLQQQLWSKS 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
naz	NP_732328.1	retinol-DH_like_SDR_c_like	50..342	CDD:212492	102/298 (34%)
DHRSX	NP_660160.2	retinol-DH_like_SDR_c_like	43..316	CDD:212492	102/299 (34%)