Protein Alignment naz and DHRS13

DIOPT Version :10

• Sequence 1: NP_732328.1
• Gene: naz / 42204
• FlyBaseID: FBgn0286852
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_653284.2
• Gene: DHRS13 / 147015
• HGNCID: 28326
• Length: 377
• Species: Homo sapiens
• Alignment Length: 389
• Identity: 116/389 - (29%)
• Similarity: 179/389 - (46%)
• Gaps: 49/389 - (12%)

  Fly    22 AALTVG-IVITVRTLMSGQRCPNDNQIKEQIVVVTGGNSGIGFEIAQALAGRGGRIILACRNLEA 85
            |.|.:| .|:....|:....|.....::.:..||||.|||||...|..||.||.|::||||:.|.
Human     8 AGLLLGAYVLVYYNLVKAPPCGGMGNLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQER 72

  Fly    86 GKRAAAIIKRELGCRTPLNSLDEDDNPEDRYFVEARYLDLCSLRSVHHFAGQLMAEFERIDVLVN 150
            |:.||..:::|.|            |.|..:..    |||.||.||..||...::...|:|:|::
Human    73 GEAAAFDLRQESG------------NNEVIFMA----LDLASLASVRAFATAFLSSEPRLDILIH 121

  Fly   151 NAGVVFANTQMPTEDGFERHSQVNYLAPFLLTHLLLPHLQRSEQGRILFVSAHAHQGAKIDF--- 212
            |||:.....   |.:.|....:||::.||||||||||.|:.....|::.|::.||...::||
Human   122 NAGISSCGR---TREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCRGRLDFKRL 183

  Fly   213 DDPLNVGTWSVKFHAREAFAHSKLCVLLATRWMARELKGTSVTVNCCTPGLVRGTRHFRNSPLMS 277
            |.|: || |..:.   .|:|.:||..:|..|.:|.:|:.|.||.....||.|......|:.|..
Human   184 DRPV-VG-WRQEL---RAYADTKLANVLFARELANQLEATGVTCYAAHPGPVNSELFLRHVPGW- 242

  Fly   278 SLCVKAVTYPWMWLFMKNAYEGAQCAIRLATDPQLKEVTGEYFNDCEIAASSVTGQDKELAKKLY 342
               ::.:..|..||.::....|||..:..|....::.::|.||.:|.:.......:|...|.:|:
Human   243 ---LRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLW 304

  Fly   343 MQTIKTLESVTKLT-------VDREEYGLDLQLEMESELRL---EEPAEAEPETETNQAADEKK 396
                   |:..:|.       .:.:|.......|..|.|..   |||..::|......:.|..|
Human   305 -------EASKRLAGLGPGEDAEPDEDPQSEDSEAPSSLSTPHPEEPTVSQPYPSPQSSPDLSK 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
naz	NP_732328.1	retinol-DH_like_SDR_c_like	50..342	CDD:212492	97/294 (33%)
DHRS13	NP_653284.2	retinol-DH_like_SDR_c_like	36..304	CDD:212492	97/295 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	309..377		11/53 (21%)