Protein Alignment naz and Hsd17b11

DIOPT Version :10

• Sequence 1: NP_732328.1
• Gene: naz / 42204
• FlyBaseID: FBgn0286852
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_444492.1
• Gene: Hsd17b11 / 114664
• MGIID: 2149821
• Length: 298
• Species: Mus musculus
• Alignment Length: 249
• Identity: 64/249 - (25%)
• Similarity: 103/249 - (41%)
• Gaps: 40/249 - (16%)

  Fly    21 IAALTVGIVITVRTLMSGQRCPNDNQIKEQIVVVTGGNSGIGFEIAQALAGRGGRIILACRNLEA 85
            |..|.:.||.::.:|:..........:..:||::||...|||...|...|....:::|...|...
Mouse     8 ILLLPLLIVFSIESLVKLFIPKKKKSVAGEIVLITGAGHGIGRLTAYEFAKLNTKLVLWDINKNG 72

  Fly    86 GKRAAAIIKRELGCRTPLNSLDEDDNPEDRYFVEARYLDLCSLR-SVHHFAGQLMAEFERIDVLV 149
            .:..||.. |:||.:.         :|   :.|:      ||.| .::..|.::..|...:.:||
Mouse    73 IEETAAKC-RKLGAQA---------HP---FVVD------CSQREEIYSAAKKVKEEVGDVSILV 118

  Fly   150 NNAGVVFANTQMPTED-GFERHSQVNYLAPFLLTHLLLPHLQRSEQGRILFVSAHAHQGAKIDFD 213
            ||||||:......|:| ..|:..:||.||.|..|...||.:.::..|.|:.|::.|
Mouse   119 NNAGVVYTADLFATQDPQIEKTFEVNVLAHFWTTKAFLPVMMKNNHGHIVTVASAA--------- 174

  Fly   214 DPLNVGTWSVKFHAREAFAHSKLCVLLATRWMARELKG---TSVTVNCCTPGLV 264
                 |...|.|..  |:..||...:...|.:..||..   |.|..:|..|..:
Mouse   175 -----GHTVVPFLL--AYCSSKFAAVGFHRALTDELAALGRTGVRTSCLCPNFI 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
naz	NP_732328.1	retinol-DH_like_SDR_c_like	50..342	CDD:212492	59/220 (27%)
Hsd17b11	NP_444492.1	17beta-HSDXI-like_SDR_c	38..277	CDD:187598	59/219 (27%)