Protein Alignment naz and RDH13

DIOPT Version :9

• Sequence 1: NP_001287387.1
• Gene: naz / 42204
• FlyBaseID: FBgn0286852
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_001139443.1
• Gene: RDH13 / 112724
• HGNCID: 19978
• Length: 331
• Species: Homo sapiens
• Alignment Length: 334
• Identity: 127/334 - (38%)
• Similarity: 193/334 - (57%)
• Gaps: 30/334 - (8%)

  Fly    19 PTIAALTV-GIVITVRTLMSGQRCPNDNQIKEQIVVVTGGNSGIGFEIAQALAGRGGRIILACRN 82
            |..|..|| |..:.::..::|..||:...|..:.|:|||.|:|||.:.|..||.|||.||||||:
Human     7 PLSALGTVAGAAVLLKDYVTGGACPSKATIPGKTVIVTGANTGIGKQTALELARRGGNIILACRD 71

  Fly    83 LEAGKRAAAIIKRELGCRTPLNSLDEDDNPEDRYFVEARYLDLCSLRSVHHFAGQLMAEFERIDV 147
            :|..:.||..|:.|     .||           :.|.||:|||.||:|:..||.:::.|.||:|:
Human    72 MEKCEAAAKDIRGE-----TLN-----------HHVNARHLDLASLKSIREFAAKIIEEEERVDI 120

  Fly   148 LVNNAGVVFANTQMP---TEDGFERHSQVNYLAPFLLTHLLLPHLQRSEQGRILFVSAHAHQGAK 209
            |:|||||:    :.|   ||||||....||:|..||||:|||..|:.|...||:.:|:.||....
Human   121 LINNAGVM----RCPHWTTEDGFEMQFGVNHLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAGH 181

  Fly   210 IDFDDPLNVGTWSV-KFHAREAFAHSKLCVLLATRWMARELKGTSVTVNCCTPGLVRGTRHFRNS 273
            ||||| ||   |.. |::.:.|:..|||.::|.|:.::|.|:|:.||||...||:.| |...|::
Human   182 IDFDD-LN---WQTRKYNTKAAYCQSKLAIVLFTKELSRRLQGSGVTVNALHPGVAR-TELGRHT 241

  Fly   274 PLMSSLCVKAVTYPWMWLFMKNAYEGAQCAIRLATDPQLKEVTGEYFNDCEIAASSVTGQDKELA 338
            .:..|........|..||.:|:....||.:..||...:|.:|:|:||:..:..|.:...:|:|:|
Human   242 GIHGSTFSSTTLGPIFWLLVKSPELAAQPSTYLAVAEELADVSGKYFDGLKQKAPAPEAEDEEVA 306

  Fly   339 KKLYMQTIK 347
            ::|:.::.:
Human   307 RRLWAESAR 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
naz	NP_001287387.1	FabG	47..318	CDD:223959	111/274 (41%)
		retinol-DH_like_SDR_c_like	50..342	CDD:212492	117/295 (40%)
RDH13	NP_001139443.1	retinol-DH_like_SDR_c	38..313	CDD:212495	118/299 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.830