Protein Alignment naz and wwox

DIOPT Version :10

• Sequence 1: NP_732328.1
• Gene: naz / 42204
• FlyBaseID: FBgn0286852
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: XP_017948987.1
• Gene: wwox / 100145151
• XenbaseID: XB-GENE-5721345
• Length: 414
• Species: Xenopus tropicalis
• Alignment Length: 313
• Identity: 105/313 - (33%)
• Similarity: 147/313 - (46%)
• Gaps: 41/313 - (13%)

  Fly    39 QRCPNDNQIKEQIVVVTGGNSGIGFEIAQALAGRGGRIILACRNLEAGKRAAAIIKRELGCRTPL 103
            |.|    .:..::|:|||.|:|||||.|::||..|..:|||||||:.|..|...|..|.
 Frog   118 QGC----DLSGKVVIVTGANTGIGFETARSLALHGTLVILACRNLQKGNEAKHKILEEW------ 172

  Fly   104 NSLDEDDNPEDRYFVEARYLDLCSLRSVHHFAGQLMAEFERIDVLVNNAGVVFANTQMPTEDGFE 168
                      .:..||...|||.|||||..||....:....:.||:.||..:....|: ||||.|
 Frog   173 ----------HKAKVEVMSLDLASLRSVQSFAEAFKSRNLALHVLICNAAYLGGPWQL-TEDGLE 226

  Fly   169 RHSQVNYLAPFLLTHLLLPHLQRSEQGRILFVSAHAHQ-------GAKIDFD--DPLNVGTWSVK 224
            ...|||:|..|.|..||...||||...|::.||:.:|:       ..|:|.:  .||....|
 Frog   227 MTFQVNHLGHFYLVSLLQDVLQRSIPSRVVVVSSESHRFTEIKDSSGKLDLNLLSPLKKDYW--- 288

  Fly   225 FHAREAFAHSKLCVLLATRWMARELKGTSVTVNCCTPGLVRGTRHFRNSPLMSSLCVKAVTYPWM 289
              |..|:..||||.:|.::.:.|.|....||.|...||.:..:...||  ......:.|:..|
 Frog   289 --AMLAYNRSKLCNILFSKELNRRLSPHGVTSNAVHPGNMMYSSIHRN--WWGYTLLFALVRP-- 347

  Fly   290 WLFMKNAYEGAQCAIRLATDPQLKEVTGEYFNDCEIAASSVTGQDKELAKKLY 342
              |.|:..:||..::..|..|:|:.:.|.|||:|.....|...|.:|.|..|:
 Frog   348 --FTKSMQQGASTSVYCAVSPELEGLGGMYFNNCCRCLPSQEAQREETAAALW 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
naz	NP_732328.1	retinol-DH_like_SDR_c_like	50..342	CDD:212492	102/300 (34%)
wwox	XP_017948987.1	WW	19..47	CDD:238122
		WW	60..90	CDD:238122
		Rossmann-fold NAD(P)(+)-binding proteins	124..407	CDD:473865	103/303 (34%)