DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PKD and CPK1

DIOPT Version :9

Sequence 1:	NP_001262705.1	Gene:	PKD / 42203	FlyBaseID:	FBgn0038603	Length:	906	Species:	Drosophila melanogaster
Sequence 2:	NP_196107.1	Gene:	CPK1 / 830366	AraportID:	AT5G04870	Length:	610	Species:	Arabidopsis thaliana

Alignment Length:	498	Identity:	128/498 - (25%)
Similarity:	210/498 - (42%)	Gaps:	102/498 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   310 GKYKSAMSSGVNLVAGRPREAPKALTNAHNSPPELVNGGLVDDSSVSGGETSKSSSDGQSEQSQS 374
            |..::.....|:....|||:.        :....:.||.:..: :|||...|:.|.:.|::..:.
plant     7 GPSRNGFLQSVSAAMWRPRDG--------DDSASMSNGDIASE-AVSGELRSRLSDEVQNKPPEQ 62

  Fly   375 STSSSPSANIPLMRIVQSVKHTKKRGGQALKEGWLVHYTSLDKAVKRYYWRLDSKTITLFVSEQG 439
            .|...|..::          .||                  |:.:     |.:||..||
plant    63 VTMPKPGTDV----------ETK------------------DREI-----RTESKPETL------ 88

  Fly   440 SKYHKELPLAELLSIESHLGDPRPECNYCFELRLPNLSYFVGQDPQVGAKEEQAVRLPPPDSGIG 504
                      |.:|:||     :||..               |:.:...|.|.... ||......
plant    89 ----------EEISLES-----KPETK---------------QETKSETKPESKPD-PPAKPKKP 122

  Fly   505 SDIAKSWETSIRQAFMHVTNTQCCES--EEQVQDMGQLYQIFPDEVLGSGQFGVVYGGVHKKTQR 567
            ..:.:.....:|           .||  :.:.::..:.|.:  ...||.||||..:..|.|.|.:
plant   123 KHMKRVSSAGLR-----------TESVLQRKTENFKEFYSL--GRKLGQGQFGTTFLCVEKTTGK 174

  Fly   568 EVAIKVIDKLRFPTKQEAQ-LKNEVAILQNIS-HCGVVNLERMFETPERIFVVMEKLK-GDMLEM 629
            |.|.|.|.|.:..|.::.: ::.|:.|:.::: |..|::::..:|....:.:|||... |::.:.
plant   175 EFACKSIAKRKLLTDEDVEDVRREIQIMHHLAGHPNVISIKGAYEDVVAVHLVMECCAGGELFDR 239

  Fly   630 ILSHARGRLSERVTKFLITQILIALKYLHSQNIVHCDLKPENVLLSSDAEFPQVKLCDFGYARII 694
            |:.  ||..:||....|...|:..::..||..::|.||||||.|..|..|...:|..|||.:...
plant   240 IIQ--RGHYTERKAAELTRTIVGVVEACHSLGVMHRDLKPENFLFVSKHEDSLLKTIDFGLSMFF 302

  Fly   695 GEKSFRRSVVGTPAYLAPEVLRNKGYNRSLDMWSVGVIIYVSLSGTFPF--NEEEDINDQIQNAA 757
            ........|||:|.|:|||||| |.|....|:||.|||:|:.|||..||  ..|:.|.:|:.:..
plant   303 KPDDVFTDVVGSPYYVAPEVLR-KRYGPEADVWSAGVIVYILLSGVPPFWAETEQGIFEQVLHGD 366

  Fly   758 FMYPPNPWKEISSNAIDLINNLLQVKQRKRYTVDKSLLHYWLQ 800
            ..:..:||..||.:|.||:..:|....:||.|..:.|.|.|:|
plant   367 LDFSSDPWPSISESAKDLVRKMLVRDPKKRLTAHQVLCHPWVQ 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PKD	NP_001262705.1	C1_1	109..154	CDD:278556
		C1	223..272	CDD:197519
		PH_PKD	396..522	CDD:269945	20/125 (16%)
		STKc_PKD	539..798	CDD:270984	89/263 (34%)
		S_TKc	547..799	CDD:214567	88/256 (34%)
CPK1	NP_196107.1	STKc_CAMK	149..407	CDD:270687	89/262 (34%)
CPK1	NP_196107.1	PTZ00184	444..586	CDD:185504
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000