DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18600 and rpa49

DIOPT Version :9

Sequence 1:	NP_650708.1	Gene:	CG18600 / 42201	FlyBaseID:	FBgn0038601	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_594382.1	Gene:	rpa49 / 2541914	PomBaseID:	SPAC2F3.03c	Length:	425	Species:	Schizosaccharomyces pombe

Alignment Length:	413	Identity:	86/413 - (20%)
Similarity:	158/413 - (38%)	Gaps:	91/413 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 PTILKFQNGSLLGDADFSMVESTVDGKKHALVYAGDQVYTGEVKDSEEVDTYIFIRNKLTNKVKV 84
            |...:||   ||..::.|..::::.|:...:.:......|..|    |.:..:.:.:|.....|:
pombe    47 PENTRFQ---LLKKSNQSNRDASLIGRTERVQFEAKNQSTATV----EANYCLAVADKTGRVKKI 104

  Fly    85 VPV-------QEALMYNHVYKKLERQKRT-GPTMSREHANKKLLKEFGGRKASRFVDNREQMMVN 141
            ||.       :..|......|.|:::..| ..|:..:.||..|  .||.||:.:.:.......|.
pombe   105 VPAKYLNTFERNILALQEKDKFLKKKHGTVSGTVMEQRANLGL--AFGTRKSQKAIMEESANRVK 167

  Fly   142 VEVMRQDLDETVNSSMLNEDEEDGTLGDVSINNEEYLASIVPEFNKEATKVDEVYAVESLIPSSL 206
            .|.:....|:.| |::....|...|..|::....:  ...:|..|..|..:::.|.:|.:||
pombe   168 AETLGDVKDQLV-SNVQKATEALPTQEDIAAAQAQ--DRPIPPVNVGAESIEDAYKLEDIIP--- 226

  Fly   207 LERLEEEAKVVFSTPVQTLPIKSEYLK--------------SCLAKIQENPVSSKRDFLHIKLII 257
                :||...::..|:...|.:..:.|              ..|..|:|  |..||    .:::.
pombe   227 ----KEEFSAIYIKPLLENPDERNWAKLLPYRHSLFINERFQRLLSIEE--VDQKR----ARILY 281

  Fly   258 YMDALQSLISLRSRQMQKAELSGITEKIENDIRHRFADP------NVAKKGTRT------NFSS- 309
            |:..||:.:..| |.:...|          .:|.:.|||      .:.|:.|:|      ..||
pombe   282 YISLLQAFLFSR-RSVGNRE----------TLRKKLADPPEILIDGLIKRFTQTTGIGSVQVSSR 335

  Fly   310 --EKALTHFIVMALLLSEKFEVDINVLSRAL--ATTKA---------RIKQYAHI------VNAL 355
              :|.:.:.:|:.|:: :.:..|:..|:..|  .|.||         ||..|...      :|..
pombe   336 EVDKIICYILVLCLIV-DNYSTDVLTLANDLNVKTMKANELFRTVGCRIMAYTETQRMALGLNKT 399

  Fly   356 PKSNSDILSLRLPSKVPALKSGR 378
            ...|.....|::|.:.|..:.||
pombe   400 DAKNHKRAVLKIPLEFPKPRRGR 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18600	NP_650708.1	RNA_pol_I_A49	33..379	CDD:284324	81/400 (20%)
rpa49	NP_594382.1	RNA_pol_I_A49	47..423	CDD:284324	86/413 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR14440
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000