Protein Alignment CG7142 and KLK4

DIOPT Version :10

• Sequence 1: NP_650703.1
• Gene: CG7142 / 42194
• FlyBaseID: FBgn0038595
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 70/248 - (28%)
• Similarity: 112/248 - (45%)
• Gaps: 31/248 - (12%)

  Fly    85 EATPHSAPYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHCLSSPQAVENSVIVA-GSHDIHDQ 148
            :.:|||.|:..::.|   :..|  :|:|.:::..|:|:||||.      :||..:. |.|.:...
Human    36 DCSPHSQPWQAALVM---ENEL--FCSGVLVHPQWVLSAAHCF------QNSYTIGLGLHSLEAD 89

  Fly   149 KGEASNIQMRHIDYYVRHELYLGGVNPYDIALIYTKEPLVFDTYVQPATLPEQDAQPEGYGTLYG 213
            :...|  ||......|||..|...:...|:.||...|.:.....::..::..|.........:.|
Human    90 QEPGS--QMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLVSG 152

  Fly   214 WGNVSMTAVPNYPHRLQEANMPILDMELCEQILARSGLPL-HETNLCTGPLTGGVSICTADSGGP 277
            ||   :.|....|..||..|:.::..|:|.::..    || |.:..|.|........|..|||||
Human   153 WG---LLANGRMPTVLQCVNVSVVSEEVCSKLYD----PLYHPSMFCAGGGQDQKDSCNGDSGGP 210

  Fly   278 LIQQCCEEHFEQANIVIGIVSWGKMPCGQKNAPSVFVRVSAFTEWINQVISTA 330
            ||   |..:.:      |:||:||.||||...|.|:..:..|||||.:.:..:
Human   211 LI---CNGYLQ------GLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	70/242 (29%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	70/242 (29%)