DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7142 and TMPRSS11D

DIOPT Version :10

Sequence 1:NP_650703.1 Gene:CG7142 / 42194 FlyBaseID:FBgn0038595 Length:334 Species:Drosophila melanogaster
Sequence 2:NP_004253.1 Gene:TMPRSS11D / 9407 HGNCID:24059 Length:418 Species:Homo sapiens


Alignment Length:252 Identity:76/252 - (30%)
Similarity:118/252 - (46%) Gaps:26/252 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    78 KKFLAKREATPHSAPYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHCLSSPQAVENSVIVAGS 142
            ::.|...||...|.|:.||:::..     .|:|.|::||..||||||||..|.....:.:..:|.
Human   185 QRILGGTEAEEGSWPWQVSLRLNN-----AHHCGGSLINNMWILTAAHCFRSNSNPRDWIATSGI 244

  Fly   143 HDIHDQKGEASNIQMRHIDYYVRHELYLGGVNPYDIALIYTKEPLVFDTYVQPATLP--EQDAQP 205
            .....:      ::|| :...:.|..|....:..||||:..:..:.|...:....||  .|:..|
Human   245 STTFPK------LRMR-VRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNIPP 302

  Fly   206 EGYGTLYGWG--NVSMTAVPNYPHRLQEANMPILDMELCEQILARSGLPLHETNLCTGPLTGGVS 268
            .....:.|||  ..:...||    .|::..:.|:..::|....:.:|..| ...||.|...|||.
Human   303 GSTAYVTGWGAQEYAGHTVP----ELRQGQVRIISNDVCNAPHSYNGAIL-SGMLCAGVPQGGVD 362

  Fly   269 ICTADSGGPLIQQCCEEHFEQANIVIGIVSWGKMPCGQKNAPSVFVRVSAFTEWINQ 325
            .|..||||||:|    |...:...::||||||.. ||..:.|.|:.||:|:.:||.|
Human   363 ACQGDSGGPLVQ----EDSRRLWFIVGIVSWGDQ-CGLPDKPGVYTRVTAYLDWIRQ 414

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7142NP_650703.1 Tryp_SPc 84..326 CDD:238113 75/246 (30%)
TMPRSS11DNP_004253.1 SEA 48..146 CDD:460188
Tryp_SPc 187..415 CDD:238113 76/250 (30%)
Blue background indicates that the domain is not in the aligned region.

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