DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7142 and TMPRSS13

DIOPT Version :10

Sequence 1:NP_650703.1 Gene:CG7142 / 42194 FlyBaseID:FBgn0038595 Length:334 Species:Drosophila melanogaster
Sequence 2:NP_001070731.1 Gene:TMPRSS13 / 84000 HGNCID:29808 Length:567 Species:Homo sapiens


Alignment Length:332 Identity:89/332 - (26%)
Similarity:141/332 - (42%) Gaps:56/332 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 VLSSASSGSIQLPTVRKCG---GGRSAGAAHTMAMN----LAAYGLLENRISTLEAPRQTH---- 75
            :.||..:.|....|.::.|   ..|:...||....|    |.....::..:...|.|.|.:    
Human   249 ICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNSTIQESLHRSECPSQRYISLQ 313

  Fly    76 --------WTKKFLAKREATPHSAPYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHC--LSSP 130
                    .|.:.:....|:....|:.||:..     |..|.|.||:|:..|:||||||  ::..
Human   314 CSHCGLRAMTGRIVGGALASDSKWPWQVSLHF-----GTTHICGGTLIDAQWVLTAAHCFFVTRE 373

  Fly   131 QAVENSVIVAGSHDIHDQKGEASNIQMRHIDYYVRHELYLGGVNPYDIALIYTKEPLVFDTYVQP 195
            :.:|...:.||:.::| |..||::|.     ..:.:..|....:.|||||:...:||....::.|
Human   374 KVLEGWKVYAGTSNLH-QLPEAASIA-----EIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHP 432

  Fly   196 ATLPEQDAQPEGYGTLY---------GWGNVSMTAVPNYPHRLQEANMPILDMELCEQILARSGL 251
            |.||.       :|..:         |:|....|.....|. |:|..:.::|.:.|...|.....
Human   433 ACLPM-------HGQTFSLNETCWITGFGKTRETDDKTSPF-LREVQVNLIDFKKCNDYLVYDSY 489

  Fly   252 PLHETNLCTGPLTGGVSICTADSGGPLIQQCCEEHFEQANIVIGIVSWGKMPCGQKNAPSVFVRV 316
             |....:|.|.|.||...|..||||||:   ||::  ....:.|:.||| ..|||:|.|.|:.:|
Human   490 -LTPRMMCAGDLRGGRDSCQGDSGGPLV---CEQN--NRWYLAGVTSWG-TGCGQRNKPGVYTKV 547

  Fly   317 SAFTEWI 323
            :....||
Human   548 TEVLPWI 554

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7142NP_650703.1 Tryp_SPc 84..326 CDD:238113 75/251 (30%)
TMPRSS13NP_001070731.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..115
PHA03378 <9..148 CDD:223065
13 X 5 AA repeats of A-S-P-A-[GLQR] 9..93
4 X 5 AA repeats of T-P-P-G-R 14..68
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 131..157
SRCR_2 231..321 CDD:464747 13/71 (18%)
Tryp_SPc 325..554 CDD:214473 73/254 (29%)
Blue background indicates that the domain is not in the aligned region.

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