Protein Alignment CG7142 and C1R

DIOPT Version :10

• Sequence 1: NP_650703.1
• Gene: CG7142 / 42194
• FlyBaseID: FBgn0038595
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_001341275.1
• Gene: C1R / 715
• HGNCID: 1246
• Length: 719
• Species: Homo sapiens
• Alignment Length: 228
• Identity: 58/228 - (25%)
• Similarity: 90/228 - (39%)
• Gaps: 31/228 - (13%)

  Fly   112 GTIINEHWILTAAHCL--SSPQAVEN-SVIVAGSHDIHDQKGEASNIQMR----HIDYYVRHELY 169
            |.::.:.|||||||.|  ...:|..| |:.|...|...::..:..|..:|    |.||.......
Human   503 GALLGDRWILTAAHTLYPKEHEAQSNASLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYN 567

  Fly   170 LGGVNPYDIALIYTKEPLVFDTYVQPATLPEQDAQPEGYGTLYG---WGNVSMTAV--PNYPHRL 229
            ..|    ||||:..:..:.....:.|..||:.|       |.|.   .|.||...|  ....|.|
Human   568 FEG----DIALLELENSVTLGPNLLPICLPDND-------TFYDLGLMGYVSGFGVMEEKIAHDL 621

  Fly   230 QEANMPILDMELCEQIL-ARSGLPLHETNL-CTGPLTGGVSICTADSGGPLIQQCCEEHFEQANI 292
            :...:|:.:.:.||..| .::.:.:...|: |.|..:.....|..||||..   ...:......:
Human   622 RFVRLPVANPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDSGGVF---AVRDPNTDRWV 683

  Fly   293 VIGIVSWGKMPCGQKNAPSVFVRVSAFTEWINQ 325
            ..||||||   .|.......:.:|..:.:||.:
Human   684 ATGIVSWG---IGCSRGYGFYTKVLNYVDWIKK 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	58/228 (25%)
C1R	NP_001341275.1	CUB	41..152	CDD:214483
		FXa_inhibition	175..203	CDD:464251
		CUB	207..316	CDD:395345
		Sushi	323..385	CDD:459664
		CCP	390..461	CDD:153056
		Tryp_SPc	477..711	CDD:214473	56/224 (25%)