DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7142 and ST14

DIOPT Version :9

Sequence 1:	NP_650703.1	Gene:	CG7142 / 42194	FlyBaseID:	FBgn0038595	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_068813.1	Gene:	ST14 / 6768	HGNCID:	11344	Length:	855	Species:	Homo sapiens

Alignment Length:	243	Identity:	72/243 - (29%)
Similarity:	112/243 - (46%)	Gaps:	27/243 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 PYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHCLSSPQAVENS-----VIVAGSHDIHDQKGE 151
            |:.||:..:    |..|.|..::|:.:|:::||||....:....|     ....|.||  ..:..
Human   627 PWQVSLHAL----GQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTAFLGLHD--QSQRS 685

  Fly   152 ASNIQMRHIDYYVRHELYLGGVNPYDIALIYTKEPLVFDTYVQPATLPEQDAQ---PEGYGT-LY 212
            |..:|.|.:...:.|..:......|||||:..::|..:.:.|:|..||  ||.   |.|... :.
Human   686 APGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLP--DASHVFPAGKAIWVT 748

  Fly   213 GWGNVSMTAVPNYPHRLQEANMPILDMELCEQILARSGLPLHETNLCTGPLTGGVSICTADSGGP 277
            |||:.........  .||:..:.:::...||.:|.:...|   ..:|.|.|:|||..|..|||||
Human   749 GWGHTQYGGTGAL--ILQKGEIRVINQTTCENLLPQQITP---RMMCVGFLSGGVDSCQGDSGGP 808

  Fly   278 LIQQCCEEHFEQANIVIGIVSWGKMPCGQKNAPSVFVRVSAFTEWINQ 325
            |.....:....||    |:||||. .|.|:|.|.|:.|:..|.:||.:
Human   809 LSSVEADGRIFQA----GVVSWGD-GCAQRNKPGVYTRLPLFRDWIKE 851

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	72/243 (30%)
CG7142	NP_650703.1	Tryp_SPc	84..323	CDD:214473	70/239 (29%)
ST14	NP_068813.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		SEA	88..>171	CDD:307516
		CUB	227..332	CDD:238001
		CUB	340..444	CDD:238001
		LDLa	454..486	CDD:238060
		LDLa	488..523	CDD:238060
		LDLa	525..559	CDD:238060
		LDLa	567..602	CDD:238060
		Tryp_SPc	615..852	CDD:238113	72/243 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920