Protein Alignment CG7142 and TMPRSS3

DIOPT Version :10

• Sequence 1: NP_650703.1
• Gene: CG7142 / 42194
• FlyBaseID: FBgn0038595
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_076927.1
• Gene: TMPRSS3 / 64699
• HGNCID: 11877
• Length: 454
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 84/287 - (29%)
• Similarity: 132/287 - (45%)
• Gaps: 36/287 - (12%)

  Fly    52 AMNLAAY---GLLENRISTLEAPRQTH---WTKKFLAKREATPHSAPYVVSIQMMTPDQGLVHYC 110
            |::.:.|   |.....:.||:.....|   ::.:.:....:.....|:..|:|.    || .|.|
Human   183 ALHHSVYVREGCASGHVVTLQCTACGHRRGYSSRIVGGNMSLLSQWPWQASLQF----QG-YHLC 242

  Fly   111 AGTIINEHWILTAAHCLSSPQAVENSVIVAGSHDIHDQKGEASNIQMRH-IDYYVRHELY----L 170
            .|::|...||:|||||:......::..|..|...:.|      |....| ::..|.|..|    |
Human   243 GGSVITPLWIITAAHCVYDLYLPKSWTIQVGLVSLLD------NPAPSHLVEKIVYHSKYKPKRL 301

  Fly   171 GGVNPYDIALIYTKEPLVFDTYVQPATLPEQDAQ-PEG-YGTLYGWGNVSMTAVPNYPHRLQEAN 233
            |.    ||||:....||.|:..:||..||..:.. |:| .....|||.....|....| .|..|.
Human   302 GN----DIALMKLAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGAGDASP-VLNHAA 361

  Fly   234 MPILDMELCEQILARSGLPLHETNLCTGPLTGGVSICTADSGGPLIQQCCEEHFEQANIVIGIVS 298
            :|::..::|.......|: :..:.||.|.|||||..|..||||||:   |:|  .:...::|..|
Human   362 VPLISNKICNHRDVYGGI-ISPSMLCAGYLTGGVDSCQGDSGGPLV---CQE--RRLWKLVGATS 420

  Fly   299 WGKMPCGQKNAPSVFVRVSAFTEWINQ 325
            :| :.|.:.|.|.|:.||::|.:||::
Human   421 FG-IGCAEVNKPGVYTRVTSFLDWIHE 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	78/249 (31%)
TMPRSS3	NP_076927.1	LDLa	74..107	CDD:238060
		SRCR_2	112..210	CDD:464747	5/26 (19%)
		Tryp_SPc	216..444	CDD:214473	76/250 (30%)