Protein Alignment CG7142 and PRSS56

DIOPT Version :10

• Sequence 1: NP_650703.1
• Gene: CG7142 / 42194
• FlyBaseID: FBgn0038595
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: XP_047301387.1
• Gene: PRSS56 / 646960
• HGNCID: 39433
• Length: 635
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 83/276 - (30%)
• Similarity: 129/276 - (46%)
• Gaps: 31/276 - (11%)

  Fly    62 ENRISTLEAPRQTHWTKKFLAKREATPHSAPYVVSIQMMTPDQGLVHYCAGTIINEHWILTAAHC 126
            |.|.||....| .|  .:.:....|.|.:.|::|.:|:     |....|.|.::...|:||||||
Human    90 ERRPSTANVTR-AH--GRIVGGSAAPPGAWPWLVRLQL-----GGQPLCGGVLVAASWVLTAAHC 146

  Fly   127 -LSSPQAVENSVIVA-GSHDIHDQKGE-ASNIQMRHIDYYVRHELYLGGVNPYDIALIYTKEPLV 188
             :.:|..:..:|.:| ||      :|| |..:.:..|   :.|..:.......|:||:....|:.
Human   147 FVGAPNELLWTVTLAEGS------RGEQAEEVPVNRI---LPHPKFDPRTFHNDLALVQLWTPVS 202

  Fly   189 FDTYVQPATLPEQDAQPEGYGT---LYGWGNVSMTAVPNYPHRLQEANMPILDMELCEQILARSG 250
            .....:|..||::..:|.. ||   :.|||.:.... |. ...::||.:|:|..:.|.:.|....
Human   203 PGGSARPVCLPQEPQEPPA-GTACAIAGWGALFEDG-PE-AEAVREARVPLLSTDTCRRALGPGL 264

  Fly   251 LPLHETNLCTGPLTGGVSICTADSGGPLIQQCCEEHFEQANIVIGIVSWGKMPCGQKNAPSVFVR 315
            .|  .|.||.|.|.|||..|..||||||  .|.|.......::.|:.|||. .||:...|.|:.|
Human   265 RP--STMLCAGYLAGGVDSCQGDSGGPL--TCSEPGPRPREVLFGVTSWGD-GCGEPGKPGVYTR 324

  Fly   316 VSAFTEWINQVISTAT 331
            |:.|.:|:.:.:|.|:
Human   325 VAVFKDWLQEQMSAAS 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7142	NP_650703.1	Tryp_SPc	84..326	CDD:238113	75/247 (30%)
PRSS56	XP_047301387.1	Tryp_SPc	105..335	CDD:238113	75/251 (30%)
		PksD	<178..600	CDD:442550	53/171 (31%)